BACKGROUND: Heart failure (HF) is a complex syndrome with varied presentations and progression patterns. Traditional classification systems based on left ventricular ejection fraction (LVEF) have limitations in capturing the heterogeneity of HF. We a...
Heart failure (HF) is marked by significant morbidity, mortality, and readmission rates, highlighting a critical need for accurate assessment of treatment efficacy. The New York Heart Association (NYHA) classification, while standard, falls short in ...
BACKGROUND: The incorporation of artificial intelligence (AI) into point-of-care ultrasound (POCUS) platforms has rapidly increased. The number of B-lines present on lung ultrasound (LUS) serve as a useful tool for the assessment of pulmonary congest...
International journal of medical informatics
Feb 19, 2025
BACKGROUND: Despite the proliferation of heart failure (HF) mortality prediction models, their practical utility is limited. Addressing this, we utilized a significant dataset to develop and validate a deep learning artificial intelligence (AI) model...
Heart failure (HF) remains a significant public health challenge with high mortality rates. Machine learning (ML) techniques offer a promising approach to predict HF mortality, potentially improving clinical outcomes. However, the effectiveness of th...
Heart failure (HF) is a complex and prevalent condition, particularly in the elderly, presenting symptoms like chest tightness, shortness of breath, and dyspnea. The study aimed to improve the classification of HF subtypes and identify potential drug...
AIMS: Mortality risk after hospitalization for heart failure (HF) is high, especially in the first 90 days. This study aimed to construct a model automatically predicting 90 day post-discharge mortality using electronic health record (EHR) data 48 h ...
International journal of biological macromolecules
Feb 11, 2025
The purpose of this study was to investigate the molecular structure of NRG-1 protein and its mechanism of action in adult hypertensive heart failure. The amino acid sequence of NRG-1 protein was analyzed by bioinformatics method. High-throughput seq...
International journal of biological macromolecules
Feb 8, 2025
Oxidative stress (OS) is a pivotal mechanism driving the progression of cardiovascular diseases, particularly heart failure (HF). However, the comprehensive characterisation of OS-related genes in HF remains largely unexplored. In the present study, ...
Biochimica et biophysica acta. Molecular basis of disease
Feb 4, 2025
BACKGROUND: Despite maximal pharmacological treatment guided by clinical guidelines, the prognosis of heart failure (HF) remains poor, posing a significant public health burden. This necessitates uncovering novel pathological and cardioprotective pat...
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