AIMC Topic: Hepatitis B, Chronic
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Machine-learning methodologies to predict disease progression in chronic hepatitis B in Africa.
Hepatology communications
Nov 15, 2024
BACKGROUND: Little is known about the determinants of disease progression among African patients with chronic HBV infection.
Machine learning models to further identify advantaged populations that can achieve functional cure of chronic hepatitis B virus infection after receiving Peg-IFN alpha treatment.
International journal of medical informatics
Oct 22, 2024
OBJECTIVE: Functional cure is currently the highest goal of hepatitis B virus(HBV) treatment.Pegylated interferon(Peg-IFN) alpha is an important drug for this purpose,but even in the hepatitis B e antigen(HBeAg)-negative population,there is still a p...
Screening of genes co-associated with osteoporosis and chronic HBV infection based on bioinformatics analysis and machine learning.
Frontiers in immunology
Sep 16, 2024
OBJECTIVE: To identify HBV-related genes (HRGs) implicated in osteoporosis (OP) pathogenesis and develop a diagnostic model for early OP detection in chronic HBV infection (CBI) patients.
A machine learning model to predict liver-related outcomes after the functional cure of chronic hepatitis B.
Journal of hepatology
Aug 31, 2024
BACKGROUND & AIMS: The risk of hepatocellular carcinoma (HCC) and hepatic decompensation persists after hepatitis B surface antigen (HBsAg) seroclearance. This study aimed to develop and validate a machine learning model to predict the risk of liver-...
Development of machine learning-based personalized predictive models for risk evaluation of hepatocellular carcinoma in hepatitis B virus-related cirrhosis patients with low levels of serum alpha-fetoprotein.
Annals of hepatology
Aug 15, 2024
INTRODUCTION AND OBJECTIVES: The increasing incidence of hepatocellular carcinoma (HCC) in China is an urgent issue, necessitating early diagnosis and treatment. This study aimed to develop personalized predictive models by combining machine learning...
Machine Learning-Based Models for Advanced Fibrosis and Cirrhosis Diagnosis in Chronic Hepatitis B Patients With Hepatic Steatosis.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Jun 19, 2024
BACKGROUND AND AIMS: The global rise of chronic hepatitis B (CHB) superimposed on hepatic steatosis (HS) warrants noninvasive, precise tools for assessing fibrosis progression. This study leveraged machine learning (ML) to develop diagnostic models f...
A machine learning-based model analysis for serum markers of liver fibrosis in chronic hepatitis B patients.
Scientific reports
May 27, 2024
Early assessment and accurate staging of liver fibrosis may be of great help for clinical diagnosis and treatment in patients with chronic hepatitis B (CHB). We aimed to identify serum markers and construct a machine learning (ML) model to reliably p...
Clinical cure induced by pegylated interferon α-2b in the advantaged population of chronic hepatitis B virus infection: a retrospective cohort study.
Frontiers in cellular and infection microbiology
Jan 16, 2024
BACKGROUND: Among the advantaged population with clinical cure of chronic hepatitis B, chronic inactive hepatitis B virus carriers (IHCs) and nucleoside analog-experienced patients have similar serological manifestations. This study established non-i...
Serological and Molecular Characterization of Occult HBV Infection in Blood Donors from South Italy.
Viruses
Dec 31, 2023
Despite good vaccine coverage and careful blood donor selection policies, hepatitis B virus (HBV) is still the most frequent viral infection among blood donors (BDs) in Italy, mostly in the occult form (OBI). We studied the virological features of OB...
Prognostic role of computed tomography analysis using deep learning algorithm in patients with chronic hepatitis B viral infection.
Clinical and molecular hepatology
Aug 29, 2023
BACKGROUND/AIMS: The prediction of clinical outcomes in patients with chronic hepatitis B (CHB) is paramount for effective management. This study aimed to evaluate the prognostic value of computed tomography (CT) analysis using deep learning algorith...
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