AIMC Topic: Humans

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A curated knowledgebase on endocrine disrupting chemicals and their biological systems-level perturbations.

The Science of the total environment
Human well-being can be affected by exposure to several chemicals in the environment. One such group is endocrine disrupting chemicals (EDCs) that can perturb the hormonal homeostasis leading to adverse health effects. In this work, we have developed...

Engineering approaches for characterizing soft tissue mechanical properties: A review.

Clinical biomechanics (Bristol, Avon)
From cancer diagnosis to detailed characterization of arterial wall biomechanics, the elastic property of tissues is widely studied as an early sign of disease onset. The fibrous structural features of tissues are a direct measure of its health and f...

Deep learning reveals untapped information for local white-matter fiber reconstruction in diffusion-weighted MRI.

Magnetic resonance imaging
PURPOSE: Diffusion-weighted magnetic resonance imaging (DW-MRI) is of critical importance for characterizing in-vivo white matter. Models relating microarchitecture to observed DW-MRI signals as a function of diffusion sensitization are the lens thro...

If machines can learn, who needs scientists?

Journal of magnetic resonance (San Diego, Calif. : 1997)
Machine learning has been used in NMR in for decades, but recent developments signal explosive growth is on the horizon. An obstacle to the application of machine learning in NMR is the relative paucity of available training data, despite the existen...

Artificial intelligence for assisting diagnostics and assessment of Parkinson's disease-A review.

Clinical neurology and neurosurgery
Artificial intelligence, specifically machine learning, has found numerous applications in computer-aided diagnostics, monitoring and management of neurodegenerative movement disorders of parkinsonian type. These tasks are not trivial due to high int...

Predicting lncRNA-disease associations using network topological similarity based on deep mining heterogeneous networks.

Mathematical biosciences
A kind of noncoding RNA with length more than 200 nucleotides named long noncoding RNA (lncRNA) has gained considerable attention in recent decades. Many studies have confirmed that human genome contains many thousands of lncRNAs. LncRNAs play signif...

PhenPath: a tool for characterizing biological functions underlying different phenotypes.

BMC genomics
BACKGROUND: Many diseases are associated with complex patterns of symptoms and phenotypic manifestations. Parsimonious explanations aim at reconciling the multiplicity of phenotypic traits with the perturbation of one or few biological functions. For...

A preliminary study of using a deep convolution neural network to generate synthesized CT images based on CBCT for adaptive radiotherapy of nasopharyngeal carcinoma.

Physics in medicine and biology
This study aims to utilize a deep convolutional neural network (DCNN) for synthesized CT image generation based on cone-beam CT (CBCT) and to apply the images to dose calculations for nasopharyngeal carcinoma (NPC). An encoder-decoder 2D U-Net neural...

MRI-based treatment planning for proton radiotherapy: dosimetric validation of a deep learning-based liver synthetic CT generation method.

Physics in medicine and biology
Magnetic resonance imaging (MRI) has been widely used in combination with computed tomography (CT) radiation therapy because MRI improves the accuracy and reliability of target delineation due to its superior soft tissue contrast over CT. The MRI-onl...