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Estimating risk of severe neonatal morbidity in preterm births under 32 weeks of gestation.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
A large recent study analyzed the relationship between multiple factors and neonatal outcome and in preterm births. Study variables included the reason for admission, indication for delivery, optimal steroid use, gestational age, and other potential...

Multilevel Feature Representation of FDG-PET Brain Images for Diagnosing Alzheimer's Disease.

IEEE journal of biomedical and health informatics
Using a single imaging modality to diagnose Alzheimer's disease (AD) or mild cognitive impairment (MCI) is a challenging task. FluoroDeoxyGlucose Positron Emission Tomography (FDG-PET) is an important and effective modality used for that purpose. In ...
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Medical breast ultrasound image segmentation by machine learning.

Ultrasonics
Breast cancer is the most commonly diagnosed cancer, which alone accounts for 30% all new cancer diagnoses for women, posing a threat to women's health. Segmentation of breast ultrasound images into functional tissues can aid tumor localization, brea...

Contour-Seed Pairs Learning-Based Framework for Simultaneously Detecting and Segmenting Various Overlapping Cells/Nuclei in Microscopy Images.

IEEE transactions on image processing : a publication of the IEEE Signal Processing Society
In this paper, we propose a novel contour-seed pairs learning-based framework for robust and automated cell/nucleus segmentation. Automated granular object segmentation in microscopy images has significant clinical importance for pathology grading of...
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Neuro-cognitive mechanisms of global Gestalt perception in visual quantification.

NeuroImage
Recent neuroimaging studies identified posterior regions in the temporal and parietal lobes as neuro-functional correlates of subitizing and global Gestalt perception. Beyond notable overlap on a neuronal level both mechanisms are remarkably similar ...

Artificial intelligence in drug design.

Science China. Life sciences
Thanks to the fast improvement of the computing power and the rapid development of the computational chemistry and biology, the computer-aided drug design techniques have been successfully applied in almost every stage of the drug discovery and devel...

Network-Based Drug Discovery: Coupling Network Pharmacology with Phenotypic Screening for Neuronal Excitability.

Journal of molecular biology
Diseases such as chronic pain with complex etiologies are unlikely to respond to single, target-specific therapeutics but rather require intervention at multiple points within a perturbed disease system. Such approaches are being enabled by the rise ...

Referenceless distortion correction of gradient-echo echo-planar imaging under inhomogeneous magnetic fields based on a deep convolutional neural network.

Computers in biology and medicine
Single-shot gradient-echo echo-planar imaging (GE-EPI) plays a significant role in applications where high temporal resolution is necessary. However, GE-EPI is susceptible to inhomogeneous magnetic fields that will cause image distortion. Most existi...
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Kernel-Based Microfluidic Constriction Assay for Tumor Sample Identification.

ACS sensors
A high-throughput multiconstriction microfluidic channels device can distinguish human breast cancer cell lines (MDA-MB-231, HCC-1806, MCF-7) from immortalized breast cells (MCF-10A) with a confidence level of ∼81-85% at a rate of 50-70 cells/min bas...