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Label-free screening of foodborne Salmonella using surface plasmon resonance imaging.

Analytical and bioanalytical chemistry
It is estimated that 95% of the foodborne infections are caused by 15 major pathogens. Therefore, rapid and effective multiplex screening techniques for these pathogens with improved efficiencies could benefit public health at lower costs. Surface pl...

High-normal albuminuria and incident chronic kidney disease in a male nondiabetic population.

Clinical and experimental nephrology
BACKGROUND: High-normal albuminuria is an important risk factor for incident chronic kidney disease in diabetic populations, in contrast to an uncertain association in nondiabetic populations. This study aimed to reveal the relationship between high-...

Classifying clinical notes with pain assessment using machine learning.

Medical & biological engineering & computing
Pain is a significant public health problem, affecting millions of people in the USA. Evidence has highlighted that patients with chronic pain often suffer from deficits in pain care quality (PCQ) including pain assessment, treatment, and reassessmen...
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Stroke Volume Recruitability during the Third Trimester of Pregnancy.

American journal of perinatology
OBJECTIVE: It is unknown whether the heart operates in the ascending or flat portion of the Starling curve during normal pregnancy. Pregnant women do not respond to the passive leg-raising maneuver secondary to mechanical obstruction of the inferior ...
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Deep learning reveals Alzheimer's disease onset in MCI subjects: Results from an international challenge.

Journal of neuroscience methods
BACKGROUND: Early diagnosis of Alzheimer's disease (AD) and its onset in subjects affected by mild cognitive impairment (MCI) based on structural MRI features is one of the most important open issues in neuroimaging. Accordingly, a scientific challen...
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Anti-pandemic influenza A (H1N1) virus potential of catechin and gallic acid.

Journal of the Chinese Medical Association : JCMA
BACKGROUND: The pandemic influenza A (H1N1) virus has spread worldwide and infected a large proportion of the human population. Discovery of new and effective drugs for the treatment of influenza is a crucial issue for the global medical community. A...
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A label-free electrochemical immunosensor based on the novel signal amplification system of AuPdCu ternary nanoparticles functionalized polymer nanospheres.

Biosensors & bioelectronics
A sensitive label-free electrochemical immunosensor was designed using a novel signal amplification system for quantitative detecting hepatitis B surface antigen (HBsAg). Nitrogen-doped graphene quantum dots (N-GQDs) supported surfactant-free AuPdCu ...
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Cytotoxic activity of the bioactive principles from Ficus burtt-davyi.

Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes
Ficus burtt-davyi (Moraceae) is a medicinal plant species indigenous to Southern Africa. In this study, a phytochemical and cytotoxic investigation on F. burtt-davyi was conducted to evaluate its ethno-medicinal use. The phytochemical study of the fr...
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Ultra-sensitive LC-MS/MS method for the quantification of gemcitabine and its metabolite 2',2'-difluorodeoxyuridine in human plasma for a microdose clinical trial.

Journal of pharmaceutical and biomedical analysis
In microdose clinical trials a maximum of 100 μg of drug substance is administered to participants, in order to determine the pharmacokinetic properties of the agents. Measuring low plasma concentrations after administration of a microdose is challen...