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Evaluation of a human adenovirus viral load assay using the Altona RealStar® PCR test.

Diagnostic microbiology and infectious disease
This study evaluated the performance of the Altona Diagnostics RealStar® Adenovirus Research Use Only (RUO) real-time PCR reagents for HAdV quantitation in plasma samples from immunodeficient patients. The assay was linear from 2.30-9.17 log copies/m...

Characterizing Autoimmune Disease-associated Diffuse Large B-cell Lymphoma in a SEER-Medicare Cohort.

Clinical lymphoma, myeloma & leukemia
BACKGROUND: Severe immune dysregulation such as seen in autoimmune (AI) disease is known to act as a significant risk factor for diffuse large B-cell lymphoma (DLBCL). However, little is known about the demographics or clinical outcomes of DLBCL that...
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Learning non-linear patch embeddings with neural networks for label fusion.

Medical image analysis
In brain structural segmentation, multi-atlas strategies are increasingly being used over single-atlas strategies because of their ability to fit a wider anatomical variability. Patch-based label fusion (PBLF) is a type of such multi-atlas approaches...

Matching disease and phenotype ontologies in the ontology alignment evaluation initiative.

Journal of biomedical semantics
BACKGROUND: The disease and phenotype track was designed to evaluate the relative performance of ontology matching systems that generate mappings between source ontologies. Disease and phenotype ontologies are important for applications such as data ...

"I Treat Him as a Normal Patient": Unveiling the Normalization Coping Strategy Among Formal Caregivers of Persons With Dementia and Its Implications for Person-Centered Care.

Journal of transcultural nursing : official journal of the Transcultural Nursing Society
INTRODUCTION: Currently, 47 million people have dementia, worldwide, often requiring paid care by formal caregivers. Research regarding family caregivers suggests normalization as a model for coping with negative emotional outcomes in caring for a pe...

A Novel Method of Synovitis Stratification in Ultrasound Using Machine Learning Algorithms: Results From Clinical Validation of the MEDUSA Project.

Ultrasound in medicine & biology
Ultrasound is widely used in the diagnosis and follow-up of chronic arthritis. We present an evaluation of a novel automatic ultrasound diagnostic tool based on image recognition technology. Methods used in developing the algorithm are described else...

An automated technique to stage lower third molar development on panoramic radiographs for age estimation: a pilot study.

The Journal of forensic odonto-stomatology
BACKGROUND: Automated methods to evaluate growth of hand and wrist bones on radiographs and magnetic resonance imaging have been developed. They can be applied to estimate age in children and subadults. Automated methods require the software to (1) r...