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ToBio: Global Pathway Similarity Search Based on Topological and Biological Features.

IEEE/ACM transactions on computational biology and bioinformatics
Pathway similarity search plays a vital role in the post-genomics era. Unfortunately, pathway similarity search involves the graph isomorphism problem which is NP-complete. Therefore, efficient search algorithms are desirable. In this work, we propos...

Identifying causal mechanisms in health care interventions using classification tree analysis.

Journal of evaluation in clinical practice
RATIONALE, AIMS, AND OBJECTIVES: Mediation analysis identifies causal pathways by testing the relationships between the treatment, the outcome, and an intermediate variable that mediates the relationship between the treatment and outcome. This paper ...
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An Ultralightweight and Living Legged Robot.

Soft robotics
In this study, we describe the most ultralightweight living legged robot to date that makes it a strong candidate for a search and rescue mission. The robot is a living beetle with a wireless electronic backpack stimulator mounted on its thorax. Inhe...

Deployment of a touchless ultraviolet light robot for terminal room disinfection: The importance of audit and feedback.

American journal of infection control
Touchless ultraviolet disinfection (UVD) devices effectively reduce the bioburden of epidemiologically relevant pathogens, including Clostridium difficile. During a 25-month implementation period, UVD devices were deployed facilitywide for the termin...

Influence of facial feedback during a cooperative human-robot task in schizophrenia.

Scientific reports
Rapid progress in the area of humanoid robots offers tremendous possibilities for investigating and improving social competences in people with social deficits, but remains yet unexplored in schizophrenia. In this study, we examined the influence of ...

Efficient k-NN Implementation for Real-Time Detection of Cough Events in Smartphones.

IEEE journal of biomedical and health informatics
The potential  of telemedicine in respiratory health care has not been completely unveiled in part due to the inexistence of reliable objective measurements of symptoms such as cough. Currently available cough detectors are uncomfortable and expensiv...

Ensemble based on static classifier selection for automated diagnosis of Mild Cognitive Impairment.

Journal of neuroscience methods
BACKGROUND: Alzheimer's disease (AD) is the most common cause of neurodegenerative dementia in the elderly population. Scientific research is very active in the challenge of designing automated approaches to achieve an early and certain diagnosis. Re...

Neurocognitive Graphs of First-Episode Schizophrenia and Major Depression Based on Cognitive Features.

Neuroscience bulletin
Neurocognitive deficits are frequently observed in patients with schizophrenia and major depressive disorder (MDD). The relations between cognitive features may be represented by neurocognitive graphs based on cognitive features, modeled as Gaussian ...

Performance of a Deep-Learning Neural Network Model in Assessing Skeletal Maturity on Pediatric Hand Radiographs.

Radiology
Purpose To compare the performance of a deep-learning bone age assessment model based on hand radiographs with that of expert radiologists and that of existing automated models. Materials and Methods The institutional review board approved the study....

Collaborative targeted learning using regression shrinkage.

Statistics in medicine
Causal inference practitioners are routinely presented with the challenge of model selection and, in particular, reducing the size of the covariate set with the goal of improving estimation efficiency. Collaborative targeted minimum loss-based estima...