Humans

Showing 70471 to 70480 of 95995 articles
Clear Filters

Label-free detection of cellular drug responses by high-throughput bright-field imaging and machine learning.

Scientific reports Sep 29, 2017
In the last decade, high-content screening based on multivariate single-cell imaging has been proven effective in drug discovery to evaluate drug-induced phenotypic variations. Unfortunately, this method inherently requires fluorescent labeling which...
Paclitaxel Microfluidics High-Throughput Screening Assays Cell Shape Microscopy, Interference Image Processing, Computer-Assisted Dose-Response Relationship, Drug Antineoplastic Agents, Phytogenic MCF-7 Cells Humans Machine Learning
View on PubMed DOI

Multi-layer network utilizing rewarded spike time dependent plasticity to learn a foraging task.

PLoS computational biology Sep 29, 2017
Neural networks with a single plastic layer employing reward modulated spike time dependent plasticity (STDP) are capable of learning simple foraging tasks. Here we demonstrate advanced pattern discrimination and continuous learning in a network of s...
Action Potentials Appetitive Behavior Animals Computational Biology Neuronal Plasticity Models, Neurological Machine Learning Algorithms Feedback Humans Neural Networks, Computer
View on PubMed DOI

Real-Time Non-Invasive Detection and Classification of Diabetes Using Modified Convolution Neural Network.

IEEE journal of biomedical and health informatics Sep 28, 2017
Non-invasive diabetes prediction has been gaining prominence over the last decade. Among many human serums evaluated, human breath emerges as a promising option with acetone levels in breath exhibiting a good correlation to blood glucose levels. Such...
ROC Curve Diabetes Mellitus Equipment Design Signal Processing, Computer-Assisted Adult Male Blood Glucose Acetone Breath Tests Neural Networks, Computer Humans Algorithms Female Young Adult
View on PubMed DOI

Estimation and evaluation of linear individualized treatment rules to guarantee performance.

Biometrics Sep 28, 2017
In clinical practice, an informative and practically useful treatment rule should be simple and transparent. However, because simple rules are likely to be far from optimal, effective methods to construct such rules must guarantee performance, in ter...
Precision Medicine Depressive Disorder, Major Supervised Machine Learning Biometry Statistics as Topic Humans Decision Support Techniques Computer Simulation
View on PubMed DOI

Pneumatic Displacement of Submacular Hemorrhage with Subretinal Air and Tissue Plasminogen Activator: Initial United States Experience.

Ophthalmology. Retina Sep 28, 2017
PURPOSE: To present the initial multicenter experience of using subretinal air injection in combination with tissue plasminogen activator (tPA) at the time of pars plana vitrectomy (PPV) to displace submacular hemorrhage (SMH).
Fluorescein Angiography Injections, Intraocular Retinal Hemorrhage Vitrectomy Male Tissue Plasminogen Activator Air Middle Aged Endotamponade Time Factors United States Fibrinolytic Agents Humans Tomography, Optical Coherence Female Retrospective Studies Fundus Oculi Aged Retina Aged, 80 and over Treatment Outcome Follow-Up Studies Visual Acuity
View on PubMed DOI

Automated diagnosis of temporal lobe epilepsy in the absence of interictal spikes.

NeuroImage. Clinical Sep 28, 2017
OBJECTIVE: To diagnose and lateralise temporal lobe epilepsy (TLE) by building a classification system that uses directed functional connectivity patterns estimated during EEG periods without visible pathological activity.
Electroencephalography Female Male Electronic Data Processing Follow-Up Studies Brain Waves Area Under Curve Epilepsy, Temporal Lobe Humans Functional Laterality Machine Learning Retrospective Studies
View on PubMed DOI

Diffusion parameter mapping with the combined intravoxel incoherent motion and kurtosis model using artificial neural networks at 3 T.

NMR in biomedicine Sep 28, 2017
Artificial neural networks (ANNs) were used for voxel-wise parameter estimation with the combined intravoxel incoherent motion (IVIM) and kurtosis model facilitating robust diffusion parameter mapping in the human brain. The proposed ANN approach was...
Neural Networks, Computer Female Adult Least-Squares Analysis Humans Diffusion Magnetic Resonance Imaging Gray Matter Monte Carlo Method White Matter
View on PubMed DOI

A Deep Learning Solution for Automatic Fetal Neurosonographic Diagnostic Plane Verification Using Clinical Standard Constraints.

Ultrasound in medicine & biology Sep 28, 2017
During routine ultrasound assessment of the fetal brain for biometry estimation and detection of fetal abnormalities, accurate imaging planes must be found by sonologists following a well-defined imaging protocol or clinical standard, which can be di...
(1)
Female Ultrasonography, Prenatal Image Processing, Computer-Assisted Machine Learning Brain Pregnancy Humans Neural Networks, Computer
View on PubMed DOI

A finite element-based machine learning approach for modeling the mechanical behavior of the breast tissues under compression in real-time.

Computers in biology and medicine Sep 28, 2017
This work presents a data-driven method to simulate, in real-time, the biomechanical behavior of the breast tissues in some image-guided interventions such as biopsies or radiotherapy dose delivery as well as to speed up multimodal registration algor...
Humans Machine Learning Female Adult Imaging, Three-Dimensional Breast Finite Element Analysis Models, Biological
View on PubMed DOI

A Network Pharmacology-Based Study on the Hepatoprotective Effect of Fructus Schisandrae.

Molecules (Basel, Switzerland) Sep 28, 2017
(Wuweizi in Chinese), a common traditional Chinese herbal medicine, has been used for centuries to treat chronic liver disease. The therapeutic efficacy of Wuweizi has also been validated in clinical practice. In this study, molecular docking and ne...
Humans Hepatocytes Liver Diseases Databases, Pharmaceutical Schisandra Neural Networks, Computer Computer Simulation Protective Agents Drugs, Chinese Herbal
View on PubMed DOI
Popular Topics
Recent Journals