AIMC Topic: Humans

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Liquid Biopsy: The Challenges of a Revolutionary Approach in Oncology.

International journal of molecular sciences
Liquid biopsy has gained attention in oncology as a non-invasive diagnostic tool, offering valuable insights into tumor biology through the analysis of circulating nucleic acid (cfDNA and cfRNA), circulating tumor cells (CTCs), extracellular vesicles...

A standardized framework for robust fragmentomic feature extraction from cell-free DNA sequencing data.

Genome biology
Fragmentomics features of cell-free DNA represent promising non-invasive biomarkers for cancer diagnosis. A lack of systematic evaluation of biases in feature quantification hinders the adoption of such applications. We compare features derived from ...

Development of a non-contrast CT-based radiomics nomogram for early prediction of delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage.

BMC medical imaging
BACKGROUNDS: Delayed cerebral ischemia (DCI) is a significant complication following aneurysmal subarachnoid hemorrhage (aSAH), leading to poor prognosis and high mortality. This study developed a non-contrast CT (NCCT)-based radiomics nomogram for e...

IoT-enabled real-time health monitoring system for adolescent physical rehabilitation.

Scientific reports
This study aims to develop an intelligent system leveraging Internet of Thing (IoT) technology to enhance the precision of youth physical training monitoring and improve training outcomes. A wearable device incorporating Micro Electro Mechanical Syst...

Automated depression detection via cloud based EEG analysis with transfer learning and synchrosqueezed wavelet transform.

Scientific reports
Post-COVID-19, depression rates have risen sharply, increasing the need for early diagnosis using electroencephalogram (EEG) and deep learning. To tackle this, we developed a cloud-based computer-aided depression diagnostic (CCADD) system that utiliz...

EnsembleEdgeFusion: advancing semantic segmentation in microvascular decompression imaging with innovative ensemble techniques.

Scientific reports
Semantic segmentation involves an imminent part in the investigation of medical images, particularly in the domain of microvascular decompression, where publicly available datasets are scarce, and expert annotation is demanding. In response to this c...

Development and validation of a hypoxemia prediction model in middle-aged and elderly outpatients undergoing painless gastroscopy.

Scientific reports
Hypoxemia is a common complication associated with anesthesia in painless gastroscopy. With the aging of the social population, the number of cases of hypoxemia among middle-aged and elderly patients is increasing. However, tools for predicting hypox...

Development and validation of a multi-omics hemorrhagic transformation model based on hyperattenuated imaging markers following mechanical thrombectomy.

Scientific reports
This study aimed to develop a predictive model integrating clinical, radiomics, and deep learning (DL) features of hyperattenuated imaging markers (HIM) from computed tomography scans immediately following mechanical thrombectomy (MT) to predict hemo...

ASLDetect: Arabic sign language detection using ResNet and U-Net like component.

Scientific reports
Sign languages are essential for communication among over 430 million deaf and hard-of-hearing individuals worldwide. However, recognizing Arabic Sign Language (ArSL) in real-world settings remains challenging due to issues like background noise, lig...

Oral ENPP1 inhibitor designed using generative AI as next generation STING modulator for solid tumors.

Nature communications
Despite the STING-type-I interferon pathway playing a key role in effective anti-tumor immunity, the therapeutic benefit of direct STING agonists appears limited. In this study, we use several artificial intelligence techniques and patient-based mult...