AIMC Topic: Humans

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Uncertainty quantification for CT dosimetry based on 10 281 subjects using automatic image segmentation and fast Monte Carlo calculations.

Medical physics
BACKGROUND: Computed tomography (CT) scans are a major source of medical radiation exposure worldwide. In countries like China, the frequency of CT scans has grown rapidly, thus making available a large volume of organ dose information. With modern c...

A CNN-transformer fusion network for predicting high-grade patterns in stage IA invasive lung adenocarcinoma.

Medical physics
BACKGROUND: Invasive lung adenocarcinoma (LUAD) with the high-grade patterns (HGPs) has the potential for rapid metastasis and frequent recurrence. Therefore, accurately predicting the presence of high-grade components is crucial for doctors to devel...

Predictive models of epidermal growth factor receptor mutation in lung adenocarcinoma using PET/CT-based radiomics features.

Medical physics
BACKGROUND: Lung adenocarcinoma (LAC) comprises a substantial subset of non-small cell lung cancer (NSCLC) diagnoses, where epidermal growth factor receptor (EGFR) mutations play a pivotal role as indicators for therapeutic intervention with targeted...

Advances in AAV capsid engineering: Integrating rational design, directed evolution and machine learning.

Molecular therapy : the journal of the American Society of Gene Therapy
Adeno-associated virus (AAV) has emerged as a highly promising vector for human gene therapy due to its favorable safety profile, versatility, and ability to transduce a wide range of tissues. However, natural AAV serotypes have shortcomings, includi...

Global disparities in artificial intelligence-based mammogram interpretation for breast cancer: A scientometric analysis of representation, trends, and equity.

European journal of cancer (Oxford, England : 1990)
BACKGROUND: Breast cancer (BC) is the most frequently diagnosed cancer and the leading cause of cancer death among women worldwide. Artificial intelligence (AI) shows promise for improving mammogram interpretation, especially in resource-limited sett...

Parametric cushioning lattice insole based on finite element method and machine learning: A preliminary computational analysis.

Journal of biomechanics
The cushioning performance of insole has always been a critical consideration in its design. While the development of intelligent methods and the emergence of additive manufacturing (AM) technology have enhanced design freedom and convenience, a stan...

Identifying progression subphenotypes of Alzheimer's disease from large-scale electronic health records with machine learning.

Journal of biomedical informatics
OBJECTIVE: Identification of clinically meaningful subphenotypes of disease progression can enhance the understanding of disease heterogeneity and underlying pathophysiology. In this study, we propose a machine learning framework to identify subpheno...

Enhancing data quality in medical concept normalization through large language models.

Journal of biomedical informatics
OBJECTIVE: Medical concept normalization (MCN) aims to map informal medical terms to formal medical concepts, a critical task in building machine learning systems for medical applications. However, most existing studies on MCN primarily focus on mode...

Enhancing brain age estimation under uncertainty: A spectral-normalized neural gaussian process approach utilizing 2.5D slicing.

NeuroImage
Brain age gap, the difference between estimated brain age and chronological age via magnetic resonance imaging, has emerged as a pivotal biomarker in the detection of brain abnormalities. While deep learning is accurate in estimating brain age, the a...

Artificial intelligence applied to epilepsy imaging: Current status and future perspectives.

Revue neurologique
In recent years, artificial intelligence (AI) has become an increasingly prominent focus of medical research, significantly impacting epileptology as well. Studies on deep learning (DL) and machine learning (ML) - the core of AI - have explored their...