AIMC Topic: Hyperlipidemias

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Development of a plasminogen activator inhibitor (PAI-1) assay and comparison of plasma PAI-1 activity in hyperlipidemic/dyslipidemic dogs with either hyperadrenocorticism or diabetes mellitus, and healthy dogs.

Research in veterinary science Nov 8, 2016
Thrombosis is a serious complication of many canine diseases and may be related to decreased fibrinolytic potential. Plasminogen activator inhibitor-1 (PAI-1) is the key regulator of fibrinolysis with increased levels demonstrated in states of pro-th...
Dogs Dog Diseases Plasminogen Activator Inhibitor 1 Adrenocortical Hyperfunction Hyperlipidemias Serologic Tests Animals Male Diabetes Mellitus Humans Female Sensitivity and Specificity
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Dysfunction of endothelial progenitor cells in hyperlipidemic rats involves the increase of NADPH oxidase derived reactive oxygen species production.

Canadian journal of physiology and pharmacology Oct 20, 2016
NADPH oxidase (NOX) is a major source of reactive oxygen species (ROS) in the body and it plays a key role in mediation of oxidative injury in the cardiovascular system. The purposes of this study are to evaluate the status of NOX in endothelial prog...
Endothelial Progenitor Cells Rats, Sprague-Dawley Reactive Oxygen Species Animals Male Rats Enzyme Inhibitors Lipoproteins, LDL NADPH Oxidases Hyperlipidemias Phenotype
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Asparaginase-associated concurrence of hyperlipidemia, hyperglobulinemia, and thrombocytosis was successfully treated by centrifuge/membrane hybrid double-filtration plasmapheresis.

Journal of clinical lipidology Dec 21, 2015
Asparaginase-associated concurrence of hyperlipidemia, hyperglobulinemia, and thrombocytosis is a rare complication requiring aggressive lipoprotein apheresis, but no one of currently available lipoprotein apheresis methods can simultaneously resolve...
Humans Male Middle Aged Plasmapheresis Thrombocytosis Asparaginase Membranes, Artificial Hemostatic Disorders Treatment Outcome Centrifugation Hyperlipidemias
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Precision population analytics: population management at the point-of-care.

Journal of the American Medical Informatics Association : JAMIA Mar 1, 2021
OBJECTIVE: To present clinicians at the point-of-care with real-world data on the effectiveness of various treatment options in a precision cohort of patients closely matched to the index patient.
Machine Learning Electronic Health Records Diabetes Mellitus, Type 2 Humans Practice Guidelines as Topic Decision Making, Computer-Assisted Hypertension Evidence-Based Medicine Patient Care Management Treatment Outcome Hyperlipidemias
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Kidney dysfunction and oxidative stress in doxorubicin-induced nephrotic rat: Protective role of sesame oil.

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia Jan 1, 2021
Doxorubicin (DOX) is an antineoplastic agent which it's clinical use has been limited due to its major side effects including cardiotoxicity and nephrotic syndrome. Sesame oil (SO) is an important edible oil with many pharmacologic effects. The aim o...
Hyperlipidemias Hypoalbuminemia Sesame Oil Male Antioxidants Oxidative Stress Rats, Wistar Proteinuria Humans Kidney Rats Sulfhydryl Compounds Female Doxorubicin Animals
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Correlation Network Analysis Provides Important Modules and Pathways for Human Hyperlipidemia.

Critical reviews in eukaryotic gene expression Jan 1, 2019
Hyperlipidemia casts great threats to humans around the world. The systemic co-expression and function enrichment analysis for this disease is limited to date. This study was to identify co-expression modules to explore hyperlipidemia-associated func...
Gene Ontology Ubiquitination Humans Cluster Analysis Databases, Factual Hyperlipidemias Gene Regulatory Networks
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The dose-response association between estimated glomerular filtration rate and prognosis of patients with ST-segment elevation myocardial infarction from rural areas of China's Liaoning province.

Medicine Dec 1, 2017
We aimed to investigate the dose-response associations between chronic kidney disease (CKD), and short and long-term cardiovascular outcomes, to characterize these associations by drawing dose-response curves based on a Chinese rural ST-segment eleva...
Aged Aged, 80 and over Adult Middle Aged Comorbidity Male Cardiovascular Diseases Biomarkers Renal Insufficiency, Chronic Prognosis Glomerular Filtration Rate Female Age Factors Humans Logistic Models Drosophila Proteins ST Elevation Myocardial Infarction Severity of Illness Index Membrane Proteins Proportional Hazards Models Hyperlipidemias China Rural Population Hospital Mortality
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Caffeoylquinic Acids Rich versus Poor Fractions of Gynura procumbens: Their Comparative Antihyperlipidemic and Antioxidant Potential.

Current pharmaceutical biotechnology Jan 1, 2017
BACKGROUND: Ethanolic extract of G. procumbens leaves has been previously shown to possess antihyperlipidemic effects.
Animals Male Antioxidants Disease Models, Animal Plant Leaves Hyperlipidemias Hypolipidemic Agents Plant Extracts Ethanol Rats, Sprague-Dawley Quinic Acid Asteraceae
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