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Hypothermia, Induced

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Therapeutic hypothermia in patients with coagulopathy following severe traumatic brain injury.

Scandinavian journal of trauma, resuscitation and emergency medicine
BACKGROUND: Coagulopathy in traumatic brain injury (TBI) has been associated with poor neurological outcomes and higher in-hospital mortality. In general principle of trauma management, hypothermia should be prevented as it directly worsens coagulopa...

Intra-Abdominal Cooling System Limits Ischemia-Reperfusion Injury During Robot-Assisted Renal Transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Robot-assisted kidney transplantation is feasible; however, concerns have been raised about possible increases in warm ischemia times. We describe a novel intra-abdominal cooling system to continuously cool the kidney during the procedure. Porcine ki...

A Randomized Control Trial Of Anti-Inflammatory Regional Hypothermia On Urinary Continence During Robot-Assisted Radical Prostatectomy.

Scientific reports
The present study seeks to present a single-blind, randomized control trial of a hypothermic anti-inflammatory device, the endorectal cooling balloon (ECB), to assess whether regional hypothermia could improve 90-day and time to pad-free continence f...

A machine learning based model for Out of Hospital cardiac arrest outcome classification and sensitivity analysis.

Resuscitation
BACKGROUND: Out-of-hospital cardiac arrest (OHCA) affects nearly 400,000 people each year in the United States of which only 10% survive. Using data from the Cardiac Arrest Registry to Enhance Survival (CARES), and machine learning (ML) techniques, w...

2D Wavelet Scalogram Training of Deep Convolutional Neural Network for Automatic Identification of Micro-Scale Sharp Wave Biomarkers in the Hypoxic-Ischemic EEG of Preterm Sheep.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
We have recently demonstrated that micro-scale Sharp waves in the first few hours EEG of asphyxiated preterm fetal sheep models are the reliable prognostic biomarkers for Hypoxic-Ischemic Encephalopathy (HIE). Higher number of sharp waves within the ...

Artificial neural networks improve early outcome prediction and risk classification in out-of-hospital cardiac arrest patients admitted to intensive care.

Critical care (London, England)
BACKGROUND: Pre-hospital circumstances, cardiac arrest characteristics, comorbidities and clinical status on admission are strongly associated with outcome after out-of-hospital cardiac arrest (OHCA). Early prediction of outcome may inform prognosis,...

A chronotherapeutics-applicable multi-target therapeutics based on AI: Example of therapeutic hypothermia.

Briefings in bioinformatics
Nowadays, the complexity of disease mechanisms and the inadequacy of single-target therapies in restoring the biological system have inevitably instigated the strategy of multi-target therapeutics with the analysis of each target individually. Howeve...

Automated Neuroprognostication Via Machine Learning in Neonates with Hypoxic-Ischemic Encephalopathy.

Annals of neurology
OBJECTIVES: Neonatal hypoxic-ischemic encephalopathy is a serious neurologic condition associated with death or neurodevelopmental impairments. Magnetic resonance imaging (MRI) is routinely used for neuroprognostication, but there is substantial subj...

Machine learning based clinical decision tool to predict acute kidney injury and survival in therapeutic hypothermia treated neonates.

Scientific reports
Therapeutic hypothermia (TH) significantly reduces mortality and morbidities in neonates with Neonatal Encephalopathy (NE). NE may result in neonatal death and multisystem organ impairment, including acute kidney injury (AKI). Our study aimed to util...