BACKGROUND: Kidney transplantation is the preferred treatment for end-stage kidney disease (ESKD) in the United States, yet access and outcomes vary by insurance type, race, and socioeconomic status. This systematic review synthesizes U.S.-based evid...
European journal of drug metabolism and pharmacokinetics
May 8, 2025
BACKGROUND AND OBJECTIVE: Model-informed precision dosing (MIPD), based on a Bayesian approach and machine learning (ML) algorithms, is a suitable approach to personalize dosage recommendations and to improve the concentration target attainment for e...
International journal of health geographics
Apr 28, 2025
BACKGROUND: Illicit kidney trade networks, operating globally, involve intricate interactions among various players, most notably buyers, sellers, brokers, and surgeons. A comprehensive understanding of these trade networks is, however, hindered by t...
BACKGROUND: Hospital readmission following renal transplantation significantly impacts patient outcomes and healthcare resources. While machine learning approaches offer promising solutions for risk prediction, their clinical application often lacks ...
Current opinion in organ transplantation
Apr 2, 2025
PURPOSE OF REVIEW: Despite the introduction of many new immunosuppressive medications, allograft rejection remains a significant complication in transplantation. The use of "liquid biopsy" to evaluate allograft function and detect early rejection has...
BMC medical informatics and decision making
Mar 21, 2025
BACKGROUND: Survival analysis is a critical tool in transplantation studies. The integration of machine learning techniques, particularly the Random Survival Forest (RSF) model, offers potential enhancements to predictive modeling and decision-making...
BACKGROUND AND OBJECTIVE: Natural language processing (NLP) is a subfield of artificial intelligence that enables computers to process human language. As most human interactions today involve the internet and electronic devices, NLP tools quickly bec...
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Mar 6, 2025
Disparities in access to the organ transplant waitlist are well-documented, but research into modifiable factors has been limited due to a lack of access to organized prewaitlisting data. This study aimed to develop a natural language processing (NLP...
BACKGROUND: Acute kidney injury (AKI) after kidney transplantation is one of the main causes of graft loss and poor patient prognosis, and it is important to explore new targets for treating AKI in kidney transplantation.
BMC medical informatics and decision making
Feb 3, 2025
INTRODUCTION: Renal transplantation is a critical treatment for end-stage renal disease, but graft failure remains a significant concern. Accurate prediction of graft survival is crucial to identify high-risk patients. This study aimed to develop pro...
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