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Kidney Transplantation

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Deciphering the impact of senescence in kidney transplant rejection: An integrative machine learning and multi-omics analysis via bulk and single-cell RNA sequencing.

PloS one
BACKGROUND: The demographic shift towards an older population presents significant challenges for kidney transplantation (KTx), particularly due to the vulnerability of aged donor kidneys to ischemic damage, delayed graft function, and reduced graft ...

Predicting graft survival in paediatric kidney transplant recipients using machine learning.

Pediatric nephrology (Berlin, Germany)
BACKGROUND: Identification of factors that affect graft survival in kidney transplantation can increase graft survival and reduce mortality. Artificial intelligence modelling enables impartial evaluation of clinician bias. This study aimed to examine...

An integrated machine learning model enhances delayed graft function prediction in pediatric renal transplantation from deceased donors.

BMC medicine
BACKGROUND: Kidney transplantation is the optimal renal replacement therapy for children with end-stage renal disease; however, delayed graft function (DGF), a common post-operative complication, may negatively impact the long-term outcomes of both t...

Machine learning analysis of contrast-enhanced ultrasound (CEUS) for the diagnosis of acute graft dysfunction in kidney transplant recipients.

Medical ultrasonography
AIM: The aim of the study was to develop machine learning algorithms (MLA) for diagnosing acute graft dysfunction (AGD) in kidney transplant recipients based on contrast-enhanced ultrasound (CEUS) analysis of the graft.Materials and methods: This pro...

AI-assisted patient education: Challenges and solutions in pediatric kidney transplantation.

Patient education and counseling
We are writing in response to the recent publication on the use of artificial intelligence, particularly ChatGPT, in generating educational materials for pediatric kidney transplant patients (Patient Education and Counseling, Volume 129, 2024). The s...

Predicting the risk of pulmonary infection after kidney transplantation using machine learning methods: a retrospective cohort study.

International urology and nephrology
PURPOSE: Pulmonary infection is the most common and serious complication after kidney transplantation that affects the survival of the transplanted kidney and the quality of life of patients. This study aims to construct a machine learning model for ...

The role of artificial intelligence measured preoperative kidney volume in predicting kidney function loss in elderly kidney donors: a multicenter cohort study.

International journal of surgery (London, England)
BACKGROUND: The increasing use of kidneys from elderly donors raises concerns due to age-related nephron loss. Combined with nephrectomy, this loss of nephrons markedly increases the risk of developing chronic kidney disease (CKD). This study aimed t...

Predicting prognostic factors in kidney transplantation using a machine learning approach to enhance outcome predictions: a retrospective cohort study.

International journal of surgery (London, England)
BACKGROUND: Accurate forecasting of clinical outcomes after kidney transplantation is essential for improving patient care and increasing the success rates of transplants. The authors' study employs advanced machine learning (ML) algorithms to identi...

Improved survival prediction for kidney transplant outcomes using artificial intelligence-based models: development of the UK Deceased Donor Kidney Transplant Outcome Prediction (UK-DTOP) Tool.

Renal failure
The UK Deceased Donor Kidney Transplant Outcome Prediction (UK-DTOP) Tool, developed using advanced artificial intelligence (AI), significantly enhances the prediction of outcomes for deceased-donor kidney transplants in the UK. This study analyzed d...