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Knowledge Bases

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Validation of the Behavior of a Knowledge Base Implementing Clinical Guidelines for Point-of-Care Antiretroviral Toxicity Monitoring.

AMIA ... Annual Symposium proceedings. AMIA Symposium
This study investigated the automated detection of antiretroviral toxicities in structured electronic health records data. The evaluation compared responses generated by 5 clinical pharmacists and 1 prototype knowledge-based application for 15 random...

Agronomic Linked Data (AgroLD): A knowledge-based system to enable integrative biology in agronomy.

PloS one
Recent advances in high-throughput technologies have resulted in a tremendous increase in the amount of omics data produced in plant science. This increase, in conjunction with the heterogeneity and variability of the data, presents a major challenge...

Fluid and electrolyte balance-establishing the knowledge base of Foundation Year One doctors.

Irish journal of medical science
BACKGROUND: Fluid and electrolyte management for hospital inpatients has been identified by multiple reports to be suboptimal, with delegation of this task to the most junior members of a medical team, Foundation Year One (FY1) doctors, also known as...

Assessment of specific versus combined purpose knowledge based models in prostate radiotherapy.

Journal of applied clinical medical physics
Knowledge-based planning (KBP) can be used to improve plan quality, planning speed, and reduce the inter-patient plan variability. KPB may also identify and reduce systematic variations in VMAT plans, something very important in multi-institutional c...

CamurWeb: a classification software and a large knowledge base for gene expression data of cancer.

BMC bioinformatics
BACKGROUND: The high growth of Next Generation Sequencing data currently demands new knowledge extraction methods. In particular, the RNA sequencing gene expression experimental technique stands out for case-control studies on cancer, which can be ad...

Novel knowledge-based system with relation detection and textual evidence for question answering research.

PloS one
With the development of large-scale knowledge bases (KBs), knowledge-based question answering (KBQA) has become an important research topic in recent years. The key task in KBQA is relation detection, which is the process of finding a compatible answ...

HLBS-PopOmics: an online knowledge base to accelerate dissemination and implementation of research advances in population genomics to reduce the burden of heart, lung, blood, and sleep disorders.

Genetics in medicine : official journal of the American College of Medical Genetics
Recent dramatic advances in multiomics research coupled with exponentially increasing volume, complexity, and interdisciplinary nature of publications are making it challenging for scientists to stay up-to-date on the literature. Strategies to addres...

Linked open data-based framework for automatic biomedical ontology generation.

BMC bioinformatics
BACKGROUND: Fulfilling the vision of Semantic Web requires an accurate data model for organizing knowledge and sharing common understanding of the domain. Fitting this description, ontologies are the cornerstones of Semantic Web and can be used to so...

DES-Mutation: System for Exploring Links of Mutations and Diseases.

Scientific reports
During cellular division DNA replicates and this process is the basis for passing genetic information to the next generation. However, the DNA copy process sometimes produces a copy that is not perfect, that is, one with mutations. The collection of ...

Drug-drug interaction extraction from biomedical texts using long short-term memory network.

Journal of biomedical informatics
The simultaneous administration of multiple drugs increases the probability of interaction among them, as one drug may affect the activities of others. This interaction among drugs may have a positive or negative impact on the therapeutic outcomes. T...