AIMC Topic: Knowledge Bases
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CMGene: A literature-based database and knowledge resource for cancer metastasis genes.
Journal of genetics and genomics = Yi chuan xue bao
May 4, 2017
ADMETNet: The knowledge base of pharmacokinetics and toxicology network.
Journal of genetics and genomics = Yi chuan xue bao
May 3, 2017
ChloroKB: A Web Application for the Integration of Knowledge Related to Chloroplast Metabolic Network.
Plant physiology
Apr 25, 2017
Higher plants, as autotrophic organisms, are effective sources of molecules. They hold great promise for metabolic engineering, but the behavior of plant metabolism at the network level is still incompletely described. Although structural models (sto...
Impact of knowledge-based iterative model reconstruction on myocardial late iodine enhancement in computed tomography and comparison with cardiac magnetic resonance.
The international journal of cardiovascular imaging
Apr 13, 2017
We evaluated the image quality and diagnostic performance of late iodine enhancement computed tomography (LIE-CT) with knowledge-based iterative model reconstruction (IMR) for the detection of myocardial infarction (MI) in comparison with late gadoli...
Computed Tomography Angiography
Coronary Circulation
Myocardial Perfusion Imaging
Knowledge Bases
Observer Variation
Multidetector Computed Tomography
Iopamidol
Gadolinium DTPA
Magnetic Resonance Imaging, Cine
Cardiac-Gated Imaging Techniques
Predictive Value of Tests
Myocardium
Coronary Angiography
Radiographic Image Interpretation, Computer-Assisted
Coronary Artery Disease
Myocardial Infarction
Middle Aged
Electrocardiography
Contrast Media
Reproducibility of Results
Aged
Male
Humans
Retrospective Studies
Female
Assigning clinical codes with data-driven concept representation on Dutch clinical free text.
Journal of biomedical informatics
Apr 8, 2017
Clinical codes are used for public reporting purposes, are fundamental to determining public financing for hospitals, and form the basis for reimbursement claims to insurance providers. They are assigned to a patient stay to reflect the diagnosis and...
DES-ncRNA: A knowledgebase for exploring information about human micro and long noncoding RNAs based on literature-mining.
RNA biology
Apr 7, 2017
Noncoding RNAs (ncRNAs), particularly microRNAs (miRNAs) and long ncRNAs (lncRNAs), are important players in diseases and emerge as novel drug targets. Thus, unraveling the relationships between ncRNAs and other biomedical entities in cells are criti...
Revealing common disease mechanisms shared by tumors of different tissues of origin through semantic representation of genomic alterations and topic modeling.
BMC genomics
Mar 14, 2017
BACKGROUND: Cancer is a complex disease driven by somatic genomic alterations (SGAs) that perturb signaling pathways and consequently cellular function. Identifying patterns of pathway perturbations would provide insights into common disease mechanis...
CATTLE (CAncer treatment treasury with linked evidence): An integrated knowledge base for personalized oncology research and practice.
CPT: pharmacometrics & systems pharmacology
Mar 13, 2017
Despite the existence of various databases cataloging cancer drugs, there is an emerging need to support the development and application of personalized therapies, where an integrated understanding of the clinical factors and drug mechanism of action...
Unveiling antimicrobial peptide-generating human proteases using PROTEASIX.
Journal of proteomics
Feb 27, 2017
UNLABELLED: Extracting information from peptidomics data is a major current challenge, as endogenous peptides can result from the activity of multiple enzymes. Proteolytic enzymes can display overlapping or complementary specificity. The activity spe...
A Hybrid Knowledge-Based and Empirical Scoring Function for Protein-Ligand Interaction: SMoG2016.
Journal of chemical information and modeling
Feb 27, 2017
We present the third generation of our scoring function for the prediction of protein-ligand binding free energy. This function is now a hybrid between a knowledge-based potential and an empirical function. We constructed a diversified set of ∼1000 c...
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