AIMC Topic: Machine Learning
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Unveiling diagnostic biomarkers and therapeutic targets in lung adenocarcinoma using bioinformatics and experimental validation.
Scientific reports
Jul 2, 2025
Lung adenocarcinoma (LUAD) is a major challenge in oncology due to its complex molecular structure and generally poor prognosis. The aim of this study was to find diagnostic markers and therapeutic targets for LUAD by integrating differential gene ex...
Identification of exosome-related genes in NSCLC via integrated bioinformatics and machine learning analysis.
Scientific reports
Jul 2, 2025
Exosomes are crucial in the development of non-small cell lung cancer (NSCLC), yet exosome-associated genes in NSCLC remain insufficiently explored. The present study identified 59 exosome-associated differentially expressed genes (EA-DEGs) from the ...
Improved bio-inspired with machine learning computing approach for thyroid prediction.
Scientific reports
Jul 2, 2025
Thyroid illness is widely recognised as a prevalent health condition that can result in a range of health disorders. Thyroid illnesses, namely hypothyroidism and hyperthyroidism, are widespread worldwide and present considerable health consequences. ...
Hybrid machine learning and physics-based model for estimating lettuce (Lactuca sativa) growth and resource consumption in aeroponic systems.
Scientific reports
Jul 2, 2025
As the global population is expected to reach 10.3 billion by the mid-2080s, optimizing agricultural production and resource management is crucial. Climate change and environmental degradation further complicate these challenges, impacting crop produ...
Integrating machine learning and bioinformatics approaches to identify novel diagnostic gene biomarkers for diabetic mice.
Scientific reports
Jul 2, 2025
Diabetes is a complex metabolic disorder, and its pathogenesis involves the interplay of genetic, environmental factors, and lifestyle choices. With the rising prevalence and increasing associated chronic complications, identifying and understanding ...
Comprehensive machine learning analysis of PANoptosis signatures in multiple myeloma identifies prognostic and immunotherapy biomarkers.
Scientific reports
Jul 2, 2025
PANoptosis is closely associated with tumorigenesis and therapeutic response, yet its role in multiple myeloma (MM) remains unclear. This study analyzed bulk transcriptomic and clinical data from the TCGA and GEO databases to identify seven PANoptosi...
Cervical cancer prediction using machine learning models based on routine blood analysis.
Scientific reports
Jul 2, 2025
Cervical cancer (CC) is the fourth most common cancer among women globally. The key to preventing and treating CC is early detection, diagnosis, and treatment. This study aimed to develop an interpretable model for predicting CC risk using routine bl...
Machine learning model and hemoglobin to red cell distribution width ratio evaluates all-cause mortality in pulmonary embolism.
Scientific reports
Jul 2, 2025
The ratio of hemoglobin (Hb) to red blood cell distribution width (RDW), known as HRR, functions as an innovative indicator related to prognosis. However, whether HRR can predict the mortality for pulmonary embolism (PE) patients remains ambiguous. A...
The construction of HMME-PDT efficacy prediction model for port-wine stain based on machine learning algorithms.
Scientific reports
Jul 2, 2025
Hematoporphyrin monomethyl ether-photodynamic therapy (HMME-PDT) is a safe and effective treatment for port-wine stain (PWS). Comprehensive methods for predicting HMME-PDT efficacy based on clinical factors are lacking. This study aims to develop and...
Advanced machine learning applications in fibromyalgia to assess the relationship between 3D spinal alignment with clinical outcomes.
Scientific reports
Jul 2, 2025
This study leveraged machine learning (ML) models to explore the relationship between three-dimensional (3D) spinal alignment parameters and clinical outcomes in patients suffering from fibromyalgia syndrome (FMS). A cohort of 303 FMS patients, diagn...
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