Longitudinal serological proteomic dynamics during antiviral therapy (AVT) in chronic hepatitis B (CHB) patients with liver fibrosis remain poorly characterized. Here, using four-dimensional data-independent acquisition mass spectrometry (4D-DIA-MS),...
Distributed Collaborative Machine Learning (DCML) offers a promising alternative to address privacy concerns in centralized machine learning. Split learning (SL) and Federated Learning (FL) are two effective learning approaches within DCML. Recently,...
Immunogenic cell death (ICD) is capable of activating both innate and adaptive immune responses. In this study, we aimed to develop an ICD-related signature in glioma patients and facilitate the assessment of their prognosis and drug sensitivity. Con...
This study introduces a novel machine learning algorithm that combines natural language processing techniques, such as Word2Vec and Doc2Vec, with neural networks to identify and validate significant actions within human action sequences. Using the 20...
Machine learning is a vital tool in advancing drug development by accurately predicting the physical, chemical, and biological properties of various compounds. This study utilizes MATLAB program-based algorithms to calculate topological indices and m...
Many genome-wide studies capture isolated moments in cell differentiation or organismal development. Conversely, longitudinal studies provide a more direct way to study these kinetic processes. Here, we present an approach for modeling gene-expressio...
BACKGROUND: Early childhood development (ECD) lays the foundation for lifelong health, academic success and social well-being, yet over 250 million children in low- and middle-income countries are at risk of not reaching their developmental potential...
The American journal of sports medicine
Aug 15, 2025
BACKGROUND: Treatment decisions in patients with anterior cruciate ligament (ACL) injuries are influenced by multiple factors, such as the desire to return to sports or symptomatic instability. Identifying the differential treatment effect of ACL rec...
Journal of chemical information and modeling
Aug 15, 2025
Cyclic sulfamidates are commonly used building blocks in organic synthesis. Correct classification of their thermal criticality is crucial for the safe use of these compounds in process development and scale-up. In this study, building on our earlier...
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Aug 14, 2025
Joint machine learning models that allow synthesizing and classifying data often offer uneven performance between those tasks or are unstable to train. In this work, we depart from a set of empirical observations that indicate the usefulness of inter...
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