Defects in pre-mRNA splicing are frequently a cause of Mendelian disease. Despite the advent of next-generation sequencing, allowing a deeper insight into a patient's variant landscape, the ability to characterize variants causing splicing defects ha...
Machine learning and deep learning are rapidly finding applications in the medical imaging field. In this paper, we address the long-standing problem of metal artifacts in computed tomography (CT) images by training a dual-stream deep convolutional n...
Digital care management programs can reduce health care costs and improve quality of care. However, it is unclear how to target patients who are most likely to benefit from these programs ex ante, a shortcoming of current "risk score"-based approache...
Polymer-assisted flocculation-dewatering of mineral processing tailings (MPT) is crucial for its environmental disposal. To reduce the number of laboratory experiments, this study proposes a novel and hybrid machine learning (ML) method for the predi...
PURPOSE: Our study assessed the ability F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) radiomics to differentiate breast carcinoma from breast lymphoma using machine-learning approach.
OBJECTIVE: Prediction of acute renal failure (ARF) and paraplegia after thoracoabdominal aortic aneurysm repair (TAAAR) is helpful for decision-making during the postoperative phase. To find a more efficient method for making a prediction, we perform...
Journal of chemical theory and computation
Nov 25, 2019
Sirtuin 5 is a class III histone deacetylase that, unlike its classification, mainly catalyzes desuccinylation and demanoylation reactions. It is an interesting drug target that we use here to test new ideas for calculating reaction pathways of large...
OBJECTIVE: Temporal lobe epilepsy is a common form of epilepsy that might be amenable to surgery. However, magnetic resonance imaging (MRI)-negative hippocampal sclerosis (HS) can hamper early diagnosis and surgical intervention for patients in clini...
Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit
Nov 25, 2019
BACKGROUND: Health-related quality of life (HRQoL) and well-being refer to the positive, subjective state that is contrary to illness. HRQoL instruments include some common questionnaires, which may often be understood differently depending on the le...
OBJECTIVE: Osteoporosis is hard to detect before it manifests symptoms and complications. In this study, we evaluated machine learning models for identifying individuals with abnormal bone mineral density (BMD) through an analysis of spine X-ray feat...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.