Surface plasmon resonance (SPR) enables in situ, label-free, real-time molecular detection. However, traditional SPR biosensors require complex and precise large-scale equipment, with detection limits constrained by multiple factors, complicating and...
The mutagenicity of chemical compounds is a key consideration in toxicology, drug development, and environmental safety. Traditional methods such as the Ames test, while reliable, are time-intensive and costly. With advances in imaging and machine le...
The Journal of clinical endocrinology and metabolism
Oct 16, 2025
CONTEXT: Metabolic dysfunction-associated steatotic liver disease (MASLD) is an umbrella term for simple hepatic steatosis and the more severe metabolic dysfunction-associated steatohepatitis. The current reliance on liver biopsy for diagnosis and a ...
Protein-protein interactions (PPIs) are ubiquitous mediators of cellular functions, and their dysregulation is central to numerous pathological conditions. Traditional drug discovery strategies targeting PPIs directly have faced considerable obstacle...
Environmental pollution (Barking, Essex : 1987)
Oct 15, 2025
Diethylene glycol dibenzoate (DEGDB) is a novel environmentally friendly plasticizer. However, toxicological studies on DEGDB remain limited, and its potential harmful effects on the malignant progression of glioblastoma are still unclear. Further sy...
Wastewater greenhouse gas (GHG) emissions represent a complex system characterized by distinct spatial-temporal patterns influenced by various drivers. This study examined the spatiotemporal heterogeneity of wastewater GHG emission intensity and tota...
Due to geographical indication advantage of Hongmeiren (HMR) citrus, economically motivated origin fraud has emerged, alongside significant differences in antioxidant components. This study employed benchtop visible and near-infrared (Vis-NIR) spectr...
Bioinspired photonic hydrogels hold promise as sensors; however, their use in triple-analyte sensing optical devices has been minimally explored. Temperature, serum Fe levels, and X-ray doses are critical factors for predicting and monitoring medical...
Highland barley has shown potential in regulating blood glucose and may serve as a natural source of dipeptidyl peptidase-IV (DPP-IV) inhibitors. In this study, machine learning (Gradient Boosting Decision Trees) and virtual screening were employed t...
Understanding aroma compounds' changes during Shuixian roasting is vital for scientific guidance. This study used gas chromatography-ion mobility spectrometry (GC-IMS) and two-dimensional gas chromatography-olfactory-mass spectrometry (GC × GC-O-MS) ...
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