International journal of molecular sciences
May 20, 2025
Centrilobular hepatocyte hypertrophy is frequently observed in animal studies for chemical safety assessment. Although its toxicological significance and precise mechanism remain unknown, it is considered an adaptive response resulting from the induc...
BACKGROUND: Malnutrition is common in cancer patients and worsens treatment and prognosis. The Patient-Generated Subjective Global Assessment (PG-SGA) is the best tool to evaluate malnutrition, but it is complicated has limited its routine clinical u...
The accumulation of heavy metal(loid)s (HMs) in the soils of urban parks in industrial cities has raised global concerns because of their environmental and health impacts. However, traditional deterministic assessments commonly overlook uncertainties...
Machine learning algorithms that integrate multiple biomarkers are increasingly used in disease detection, yet economic considerations are often overlooked. Medial vascular calcification (mVC), a pathology associated with elevated cardiovascular risk...
Early diagnosis of bloodstream infection (BSI) is crucial for informed antibiotic use. This study developed a machine learning approach for early BSI detection using a comprehensive dataset from Rigshospitalet, Denmark (2010-2020). The dataset includ...
The detection of small extracellular vesicles (sEVs) is currently a pivotal liquid biopsy approach for noninvasive cancer diagnosis. However, the lack of adequate specificity and sensitivity, as well as labor-intensive purification and analysis proce...
With their important role in regulating intracellular redox balance and maintaining cell homeostasis, endogenous mercaptans are recognized as biomarkers of many diseases in clinical practice, and thus establishing efficient yet simple methods to dist...
Circulating tumor cells (CTCs) serve as valuable biomarkers in tumor circulation, carrying essential primary tumor information. The purification of CTCs from peripheral blood samples and the analysis of their characteristic molecules enable the detec...
Mass spectrometry is one of the most effective analytical methods for unknown compound identification. By comparing observed / spectra with a database of experimentally determined spectra, this process identifies compound(s) in any given sample. Unkn...
Emotion monitoring plays a crucial role in mental health management. However, traditional methods of emotion recognition predominantly rely on subjective questionnaires or facial expression analyses, which are often inadequate for continuous and high...
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