AIMC Topic: Machine Learning

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Predicting Antidepressant Treatment Response From Cortical Structure on MRI: A Mega-Analysis From the ENIGMA-MDD Working Group.

Human brain mapping
Accurately predicting individual antidepressant treatment response could expedite the lengthy trial-and-error process of finding an effective treatment for major depressive disorder (MDD). We tested and compared machine learning-based methods that pr...

TPD52 as a Therapeutic Target Identified by Machine Learning Shapes the Immune Microenvironment in Breast Cancer.

Journal of cellular and molecular medicine
Breast cancer (BRCA) is one of the most common malignancies and a leading cause of cancer-related mortality among women globally. Despite advances in diagnosis and treatment, the heterogeneity of BRCA presents significant challenges for effective man...

AI Methods for Antimicrobial Peptides: Progress and Challenges.

Microbial biotechnology
Antimicrobial peptides (AMPs) are promising candidates to combat multidrug-resistant pathogens. However, the high cost of extensive wet-lab screening has made AI methods for identifying and designing AMPs increasingly important, with machine learning...

Use of Machine Learning Models to Predict Microaspiration Measured by Tracheal Pepsin A.

American journal of critical care : an official publication, American Association of Critical-Care Nurses
BACKGROUND: Enteral feeding intolerance, a common type of gastrointestinal dysfunction leading to underfeeding, is associated with increased mortality. Tracheal pepsin A, an indicator of microaspiration, was found in 39% of patients within 24 hours o...

Diagnosis of Schizophrenia and Its Subtypes Using MRI and Machine Learning.

Brain and behavior
PURPOSE: The neurobiological heterogeneity present in schizophrenia remains poorly understood. This likely contributes to the limited success of existing treatments and the observed variability in treatment responses. Our objective was to employ magn...

Characterization of Machine Learning-Based Surrogate Models of Neural Activation Under Electrical Stimulation.

Bioelectromagnetics
Electrical stimulation of peripheral nerves via implanted electrodes has been shown to be a promising approach to restore sensation, movement, and autonomic functions across a wide range of illnesses and injuries. While in principle computational mod...

Predictive Value of Machine Learning for the Risk of In-Hospital Death in Patients With Heart Failure: A Systematic Review and Meta-Analysis.

Clinical cardiology
BACKGROUND: The efficiency of machine learning (ML) based predictive models in predicting in-hospital mortality for heart failure (HF) patients is a topic of debate. In this context, this study's objective is to conduct a meta-analysis to compare and...

Leveraging artificial intelligence for predicting spontaneous closure of perimembranous ventricular septal defect in children: a multicentre, retrospective study in China.

The Lancet. Digital health
BACKGROUND: Perimembranous ventricular septal defect (PMVSD) is a prevalent congenital heart disease, presenting challenges in predicting spontaneous closure, which is crucial for therapeutic decisions. Existing models mainly rely on structured echoc...

A Novel Effective Models for Identifying BRCA Patients and Optimizing Clinical Treatments.

Anti-cancer agents in medicinal chemistry
OBJECTIVE: This study aimed to develop an effective model that identifies high-risk breast cancer (BRCA) patients and optimizes clinical treatments.

A Machine Learning Model to Harmonize Volumetric Brain MRI Data for Quantitative Neuroradiologic Assessment of Alzheimer Disease.

Radiology. Artificial intelligence
Purpose To extend a previously developed machine learning algorithm for harmonizing brain volumetric data of individuals undergoing neuroradiologic assessment of Alzheimer disease not encountered during model training. Materials and Methods Neuroharm...