OBJECTIVE: Microsatellite instability (MSI) is a novel predictive biomarker for chemotherapy and immunotherapy response, as well as prognostic indicator in colorectal cancer (CRC). The current standard for MSI identification is polymerase chain react...
Journal of magnetic resonance imaging : JMRI
Nov 1, 2025
The low proton density and high signal decay rate of pulmonary tissue have previously hampered the application of magnetic resonance imaging (MRI) in the clinical evaluation of lung disorders. With the continuing technical advances in scanners, coils...
IEEE transactions on bio-medical engineering
Nov 1, 2025
Accurate segmentation of prostate tumors from multi-modal magnetic resonance (MR) images is crucial for the diagnosis and treatment of prostate cancer. However, the robustness of existing segmentation methods is limited, mainly because these methods ...
European heart journal. Cardiovascular Imaging
Oct 30, 2025
AIMS: Light-chain cardiac amyloidosis (AL-CA) is a progressive heart disease with high mortality rate and variable prognosis. The presently used Mayo staging method can only stratify patients into four stages, highlighting the necessity for a more in...
Suicide represents an egregious threat to society despite major advancements in medicine, in part due to limited knowledge of the biological mechanisms of suicidal behavior. We apply a connectome predictive modeling machine learning approach to ident...
The prediction and management of sudden cardiac death risk continue to pose significant challenges in cardiovascular care despite advances in therapies over the last two decades. Late gadolinium enhancement (LGE) on cardiac magnetic resonance-a marke...
The Journal of bone and joint surgery. American volume
Sep 17, 2025
BACKGROUND: Meniscal ramp lesions can impact knee stability, particularly when associated with anterior cruciate ligament (ACL) injuries. Although magnetic resonance imaging (MRI) is the primary diagnostic tool, its diagnostic accuracy remains subopt...
Journal of applied clinical medical physics
Sep 1, 2025
BACKGROUND: Deep learning (DL)-based organ segmentation is increasingly used in radiotherapy. While methods exist to generate voxel-wise uncertainty maps from DL-based auto-segmentation models, these maps are rarely presented to clinicians.
Journal of applied clinical medical physics
Sep 1, 2025
Medical imaging is fundamental to digital twin technology, enabling patient-specific virtual models of anatomy and physiology. By integrating high-resolution modalities (Magnetic Resonance Imaging (MRI), Computed Tomography (CT), Positron Emission To...
Journal of applied clinical medical physics
Sep 1, 2025
BACKGROUND: In external beam radiation therapy (EBRT) for prostate cancer, both MRI and CT are typically used-CT provides electron density for dose calculation and visualization of bony anatomy and fiducial markers, while MRI offers superior soft tis...
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