BACKGROUND: Exercise guidelines for older adults are predominantly "one-size-fits-all," primarily focusing on aerobic activity with limited emphasis on motor components.
BACKGROUND: Panic attack prediction remains a critical challenge in mental health care due to the high interindividual variability of physiological responses and the limitations of subjective psychological assessments.
BACKGROUND: Automated speech and language analysis (ASLA) is gaining momentum as a noninvasive, affordable, and scalable approach for the early detection of Alzheimer disease (AD). Nevertheless, the literature presents 2 notable limitations. First, m...
OBJECTIVE: To develop a machine-learning-based model and construct a nomogram that integrates ClinCheck features and clinical risk factors for accurately predicting open gingival embrasures (OGE) between mandibular central incisors after clear aligne...
The Journal of clinical investigation
Oct 15, 2025
Hypoxia in the tumor microenvironment promotes lymphatic metastasis, yet the role of cancer-associated fibroblasts (CAFs) in this process remains insufficiently elucidated in colorectal cancer (CRC). In this study, we developed a large language model...
Rapid and accurate quantitative assessment of muscle tissue characteristics is valuable for the diagnosis and monitoring of neuromuscular diseases (NMDs). Quantitative magnetic resonance imaging (MRI) enables non-invasive assessment of muscle patholo...
Brain-machine interface (BMI) research has shown the efficacy of using motor and sensory-related neural signals to assist physically impaired patients. Despite the comparable ability to extract more abstract cognitive signals from the brain, little e...
Artificial intelligence (AI) is transforming healthcare through tools like large language model chatbots. AI chatbots can simulate human conversation, provide personalized information, and interact with patients in real time. Their ease of use and co...
This study investigates whether individuals can learn to accurately discriminate between human-written and AI-produced texts when provided with immediate feedback, and if they can use this feedback to recalibrate their self-perceived competence. We a...
BACKGROUND: Depression is a major public health concern, with a rising prevalence among adolescents and young adults. However, the neural mechanisms underlying depressive symptoms remain poorly understood. This study aimed to identify patterns of alt...
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