Nonalcoholic fatty liver disease (NAFLD) is now the leading cause of global chronic liver disease, affecting approximately 32.4% of the population in various regions and imposing healthcare and economic burdens. The gold standard for the diagnosis of...
BACKGROUND: Glucose metabolism disorders (GMDs) are a serious global public health issue, characterized by a high incidence rate and youthfulness. GMDs contribute to the occurrence of major adverse cardiovascular events (MACEs), meanwhile with the re...
Clinical cancer research : an official journal of the American Association for Cancer Research
Jun 13, 2025
PURPOSE: Although the association between cytotoxic T lymphocytes and favorable prognosis in colorectal cancer is well established, the prognostic significance of B lymphocytes remains more ambiguous. This study aimed to assess the characteristics an...
Clinical cancer research : an official journal of the American Association for Cancer Research
Jun 13, 2025
PURPOSE: Although radiotherapy (RT) is one of the primary treatment modalities used in the treatment of cancer, patients often experience toxicity during or after treatment. RT-induced genitourinary (GU) toxicity is a significant survivorship challen...
BACKGROUND: Fibrosis is a common complication in Crohn's disease (CD), often leading to intestinal strictures. This study aims to explore the transcriptomic signature of fibrostenotic ileal CD for a comprehensive characterization of biological and ce...
BACKGROUND: Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by increased stool frequency, rectal bleeding, and urgency. To streamline the quantitative assessment of histopathology using the Nancy Index in UC patients, we...
BACKGROUND: Large language models (LLMs) are revolutionizing natural language processing, increasingly applied in clinical settings to enhance preoperative patient education.
BACKGROUND: Mosquito-borne diseases, such as malaria, dengue, and Zika, continue to pose significant threats to global health, resulting in millions of cases and thousands of deaths each year. Notably, only older mosquitoes can transmit these disease...
OBJECTIVES: Training public health personnel is crucial for enhancing the capacity of public health systems. However, existing research often falls short in providing a comprehensive theoretical framework and fails to account for the intricate interp...
Cardiovascular disease (CVD) is a primary cause of death in India, accounting for a significant portion of the global CVD burden. This study looks at statistics on heart disease mortality from the Institute for Health Metrics and Evaluation (IHME) fr...
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