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Identifying the key factors of mercury exposure in residents of southwestern Iran using machine learning algorithms.

Environmental geochemistry and health
It is necessary to predict hair mercury (Hg) levels and specify the related effective factors to develop preventive strategies to reduce Hg exposure in different regions. This study is the first effort to investigate the effectiveness of eight machin...

Development and validation of an integrated residual-recurrent neural network model for automated heart murmur detection in pediatric populations.

Scientific reports
Congenital heart disease affects approximately 1% of children worldwide, with a number of cases in resource-limited settings remaining undiagnosed through school age. While cardiac auscultation is a key screening method, its effectiveness varies wide...

A machine learning-derived angiogenesis signature for clinical prognosis and immunotherapy guidance in colon adenocarcinoma.

Scientific reports
Colon adenocarcinoma (COAD) is one of the most prevalent malignancies worldwide and its prognosis is extremely poor. Angiogenesis has been linked to clinical outcomes, tumor progression, and treatment sensitivity. However, the role of angiogenesis in...

Development and validation of a 3-D deep learning system for diabetic macular oedema classification on optical coherence tomography images.

BMJ open
OBJECTIVES: To develop and validate an automated diabetic macular oedema (DME) classification system based on the images from different three-dimensional optical coherence tomography (3-D OCT) devices.

An immunohistochemistry-based classification of colorectal cancer resembling the consensus molecular subtypes using convolutional neural networks.

Scientific reports
Colorectal cancer (CRC) represents a major global disease burden with nearly 1 million cancer-related deaths annually. TNM staging has served as the foundation for predicting patient prognosis, despite variation across staging groups. The consensus m...

Integration of Bulk RNA and Single-Cell Analyses Reveal Distinct Expression Patterns of Anoikis-Related Genes and the Immunosuppressive Role of NQO1 Macrophages in Hepatocellular Carcinoma.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Anoikis resistance plays a crucial role in the proliferation, metastasis, and invasion of hepatocellular carcinoma (HCC). However, the key genes involved remain to be identified. This study aimed to investigate the prognostic value and impact of anoi...

Deep learning reconstruction improves computer-aided pulmonary nodule detection and measurement accuracy for ultra-low-dose chest CT.

BMC medical imaging
PURPOSE: To compare the image quality and pulmonary nodule detectability and measurement accuracy between deep learning reconstruction (DLR) and hybrid iterative reconstruction (HIR) of chest ultra-low-dose CT (ULDCT).

Deep learning-driven modality imputation and subregion segmentation to enhance high-grade glioma grading.

BMC medical informatics and decision making
PURPOSE: This study aims to develop a deep learning framework that leverages modality imputation and subregion segmentation to improve grading accuracy in high-grade gliomas.