AIMC Topic: Male

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Fibroblast growth factor 5: a novel biomarker for familial hypercholesterolaemia.

European heart journal
BACKGROUND AND AIMS: Identification of individuals affected by familial hypercholesterolaemia (FH) is suboptimal when genetic tests are unavailable. Relying only on low-density lipoprotein cholesterol (LDL-C) is challenging as it may not allow distin...

M-GNN: A Graph Neural Network Framework for Lung Cancer Detection Using Metabolomics and Heterogeneous Graph Modeling.

International journal of molecular sciences
Lung cancer remains the leading cause of cancer-related mortality worldwide, with early detection critical for improving survival rates, yet conventional methods like CT scans often yield high false-positive rates. This study introduces M-GNN, a grap...

Analyzing Key Predictors of Postoperative Delirium Following Coronary Artery Bypass Grafting and Aortic Valve Replacement: A Machine Learning Perspective.

Medicina (Kaunas, Lithuania)
: Postoperative delirium (POD) is a frequent and severe complication following cardiac surgery, particularly in high-risk patients undergoing coronary artery bypass grafting (CABG) and aortic valve replacement (AVR). Despite extensive research, predi...

Transforming 3D MRI to 2D Feature Maps Using Pre-Trained Models for Diagnosis of Attention Deficit Hyperactivity Disorder.

Tomography (Ann Arbor, Mich.)
According to the World Health Organization (WHO), approximately 5% of children and 2.5% of adults suffer from attention deficit hyperactivity disorder (ADHD). This disorder can have significant negative consequences on people's lives, particularly c...

Identifying Mild-to-Moderate Atopic Dermatitis Using a Generic Machine Learning Approach: A Danish National Health Register Study.

Acta dermato-venereologica
Atopic dermatitis is a chronic skin disease, causing itching and recurrent eczematous lesions. In Danish national register data, adults with atopic dermatitis can only be identified if they have a hospital-diagnosed atopic dermatitis. The purpose of ...

Sex differences in bladder cancer: understanding biological and clinical implications.

Biology of sex differences
Bladder cancer (BC) remains a significant global health concern, with substantial sex and racial disparities in incidence, progression, and outcomes. BC is the sixth most common cancer among males and the seventeenth most common among females worldwi...

Identifying Lactylation-related biomarkers and therapeutic drugs in ulcerative colitis: insights from machine learning and molecular docking.

BMC pharmacology & toxicology
BACKGROUND: Ulcerative colitis (UC), a chronic relapsing-remitting inflammatory bowel disease. Recent studies have shown that lactylation modifications may be involved in metabolic-immune interactions in intestinal inflammation through epigenetic reg...

Development and validation of a novel predictive model for dementia risk in middle-aged and elderly depression individuals: a large and longitudinal machine learning cohort study.

Alzheimer's research & therapy
BACKGROUND: Depression serves as a prodromal symptom of dementia, and individuals with depression exhibit a significantly higher risk of developing dementia. The aim of this study is to develop and validate a novel dementia risk prediction tool among...

Machine learning approach for unmet medical needs among middle-aged adults in South Korea: a cross-sectional study.

BMC health services research
BACKGROUND: South Korea is reported to have higher levels of unmet medical needs (UMN) than other countries, particularly among the middle-aged adult population. Considering that this group constitutes a substantial portion of the country's productiv...

Optimizing unsupervised feature engineering and classification pipelines for differentiated thyroid cancer recurrence prediction.

BMC medical informatics and decision making
BACKGROUND: Differentiated thyroid cancer (DTC) is a common endocrine malignancy with rising incidence and frequent recurrence, despite a generally favorable prognosis. Accurate recurrence prediction is critical for guiding post-treatment strategies....