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Joint impact of stress hyperglycaemic ratio and glycaemic variability in patients with ischaemic stroke and machine learning for mortality prediction.

BMC neurology
BACKGROUND: The global burden of ischaemic stroke (IS) is high, which is potentially relevant to stress hyperglycemia ratio (SHR) and glycaemic variability (GV). This study aims to evaluate the combined effect of the SHR and GV with predict short-ter...

Cell-free DNA methylation and fragmentomics-based liquid biopsy for accurate esophageal cancer detection.

BMC cancer
BACKGROUND: Cell-free DNA is a promising source of biomarkers for early cancer detection and carries tumor-driven methylation and fragmentation features that have achieved good diagnostic efficacy across various cancers. However, there were no studie...

Machine learning-based clinical-radiomics model for predicting recurrence risk after radical surgery in sinonasal squamous cell carcinoma: a preliminary 2-year follow-up study.

BMC medical imaging
BACKGROUND: To construct and validate an optimal machine learning (ML)-based clinical-radiomics model integrating clinical and radiomics features for predicting recurrence risk within 2 years after radical surgery in patients with sinonasal squamous ...

Pre-operatively predicting kidney stone recurrence: integrating radiomic features and clinical variables using machine learning.

BMC medical imaging
BACKGROUND: Radiomics and artificial intelligence have shown strong predictive capabilities in urinary stone research, particularly concerning stone composition, characteristics, and treatment outcomes. However, the association of stone radiomics and...

NeuroAgeFusionNet an ensemble deep learning framework integrating CNN, transformers, and GNN for robust brain age estimation using MRI scans.

Scientific reports
Brain age prediction based on anatomical MRI scans, as an essentially new measure in neuroimaging and aging research, provides a crucial marker for the early diagnosis of neurodegenerative diseases, cognitive health appraisal, and biological age pred...

Detect pre-cancerous tongue lesions for early oral cancer diagnosis using deep learning algorithm.

Scientific reports
Precancerous tongue lesion is a prevalent, complex, and highly perilous kind of cancer. The tumour might be in the salivary glands, tonsils, neck, cheek, and mouth. Oral Cancer (OC) is commonly identified in advanced stages due to the limited accurac...

Integrated transcriptomics and proteomics reveal ferroptosis induced by B[a]P and BPDE in mouse hippocampal neurons.

Scientific reports
The environmental pollutant Benzo[a]pyrene (B[a]P) and its ultimate metabolite B[a]P-7,8-diol-9,10-epoxide (BPDE) exhibit neurotoxic effects, yet the underlying molecular mechanisms remain enigmatic. Recently, ferroptosis has emerged as a potential p...

Explainable ensemble learning for Epstein-Barr virus risk prediction in ulcerative colitis and Crohn's disease using routine biomarkers.

Scientific reports
Epstein-Barr virus (EBV) exacerbates inflammatory bowel disease (IBD) and is challenging to monitor with invasive or costly tests. We investigated whether explainable machine learning can predict EBV infection from routine clinical data in ulcerative...

Spatiotemporal multimodal emotion recognition using Temporal video sequences and pose features for child emotion classification.

Scientific reports
Developmental psychology and affective computing have placed great emphasis on identifying children's emotional cues in recent times. In this study, a novel Spatio-Temporal Multimodal Emotion Recognition Network (ST-MERN) for child emotion classifica...

Classifying schizophrenia subtypes via resting-state EEG complexity networks.

Scientific reports
Schizophrenia (SZ) is increasingly recognized as a network disorder marked by abnormal functional connectivity, yet the clinical utility of fMRI remains limited. Electroencephalography (EEG) provides a more practical alternative, though conventional ...