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Melanoma

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Geometric deep learning and multiple-instance learning for 3D cell-shape profiling.

Cell systems
The three-dimensional (3D) morphology of cells emerges from complex cellular and environmental interactions, serving as an indicator of cell state and function. In this study, we used deep learning to discover morphology representations and understan...

Artificial intelligence in dermatopathology: a systematic review.

Clinical and experimental dermatology
Medical research, driven by advancing technologies like artificial intelligence (AI), is transforming healthcare. Dermatology, known for its visual nature, benefits from AI, especially in dermatopathology with digitized slides. This review explores A...

Advances in computer vision and deep learning-facilitated early detection of melanoma.

Briefings in functional genomics
Melanoma is characterized by its rapid progression and high mortality rates, making early and accurate detection essential for improving patient outcomes. This paper presents a comprehensive review of significant advancements in early melanoma detect...

Diagnostic Power of MicroRNAs in Melanoma: Integrating Machine Learning for Enhanced Accuracy and Pathway Analysis.

Journal of cellular and molecular medicine
This study identifies microRNAs (miRNAs) with significant discriminatory power in distinguishing melanoma from nevus, notably hsa-miR-26a and hsa-miR-211, which have exhibited diagnostic potential with accuracy of 81% and 78% respectively. To enhance...

Melanoma imaging and diagnosis: What does the future hold?

Australian journal of general practice
BACKGROUND: In Australia, artificial intelligence (AI) is increasingly being used in the field of melanoma diagnosis. Early diagnosis is arguably the most important prognostic factor for melanoma survival. The use of digital monitoring of naevi, espe...

Unravelling tumour cell diversity and prognostic signatures in cutaneous melanoma through machine learning analysis.

Journal of cellular and molecular medicine
Melanoma, a highly malignant tumour, presents significant challenges due to its cellular heterogeneity, yet research on this aspect in cutaneous melanoma remains limited. In this study, we utilized single-cell data from 92,521 cells to explore the tu...

Evaluation of an artificial intelligence-based decision support for the detection of cutaneous melanoma in primary care: a prospective real-life clinical trial.

The British journal of dermatology
BACKGROUND: Use of artificial intelligence (AI), or machine learning, to assess dermoscopic images of skin lesions to detect melanoma has, in several retrospective studies, shown high levels of diagnostic accuracy on par with - or even outperforming ...