BACKGROUND: Immunotherapy has revolutionized skin cutaneous melanoma treatment, but response variability due to tumor heterogeneity necessitates robust biomarkers for predicting immunotherapy response.
Journal of imaging informatics in medicine
39284982
Cutaneous melanoma is a highly lethal form of cancer. Developing a medical image segmentation model capable of accurately delineating melanoma lesions with high robustness and generalization presents a formidable challenge. This study draws inspirati...
BACKGROUND: Risk stratification and treatment benefit prediction models are urgent to improve negative sentinel lymph node (SLN-) melanoma patient selection, thus avoiding costly and toxic treatments in patients at low risk of recurrence. To this end...
SIGNIFICANCE: Early detection of melanoma is crucial for improving patient outcomes, and dermoscopy is a critical tool for this purpose. However, hair presence in dermoscopic images can obscure important features, complicating the diagnostic process....
Skin cancer (SC) is one of the three most common cancers worldwide. Melanoma has the deadliest potential to spread to other parts of the body among all SCs. For SC treatments to be effective, early detection is essential. The high degree of similarit...
Journal of immunotherapy (Hagerstown, Md. : 1997)
39506915
In this study, we aimed to investigate disparities in the tumor immune microenvironment (TME) between primary and metastatic malignant melanoma (MM) using single-cell RNA sequencing (scRNA- seq ) and to identify metastasis-related T cell marker genes...
Early detection and treatment of skin cancer are important for patient recovery and survival. Dermoscopy images can help clinicians for timely identification of cancer, but manual diagnosis is time-consuming, costly, and prone to human error. To cond...
The color of skin lesions is a crucial diagnostic feature for identifying malignant melanoma and other skin diseases. Typical colors associated with melanocytic lesions include tan, brown, black, red, white, and blue-gray. This study introduces a nov...
Malignant melanoma is the most severe skin cancer with a rising incidence rate. Several noninvasive image techniques and computer-aided diagnosis systems have been developed to help find melanoma in its early stages. However, most previous research u...
IEEE journal of biomedical and health informatics
39302772
Melanoma is considered a global public health challenge and is responsible for more than 90% deaths related to skin cancer. Although the diagnosis of early melanoma is the main goal of dermoscopy, the discrimination between dermoscopic images of in s...