AIMC Topic: Mice
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A Robotic System for Adaptive Training and Function Assessment of Forelimb Retraction in Mice.
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Aug 8, 2018
Rodent models are decisive for translational research in healthy and pathological conditions of motor function thanks to specific similarities with humans. Here, we present an upgraded version of the M-Platform, a robotic device previously designed t...
Deep Neural Networks for In Situ Hybridization Grid Completion and Clustering.
IEEE/ACM transactions on computational biology and bioinformatics
Aug 7, 2018
Transcriptome in brain plays a crucial role in understanding the cortical organization and the development of brain structure and function. Two challenges, incomplete data and high dimensionality of transcriptome, remain unsolved. Here, we present a ...
Weakly-Supervised Convolutional Neural Network Architecture for Predicting Protein-DNA Binding.
IEEE/ACM transactions on computational biology and bioinformatics
Aug 7, 2018
Although convolutional neural networks (CNN) have outperformed conventional methods in predicting the sequence specificities of protein-DNA binding in recent years, they do not take full advantage of the intrinsic weakly-supervised information of DNA...
Cell type discrimination based on image features of molecular component distribution.
Scientific reports
Aug 6, 2018
Machine learning-based cell classifiers use cell images to automate cell-type discrimination, which is increasingly becoming beneficial in biological studies and biomedical applications. Brightfield or fluorescence images are generally employed as th...
GOATOOLS: A Python library for Gene Ontology analyses.
Scientific reports
Jul 18, 2018
The biological interpretation of gene lists with interesting shared properties, such as up- or down-regulation in a particular experiment, is typically accomplished using gene ontology enrichment analysis tools. Given a list of genes, a gene ontology...
Organization of Neural Population Code in Mouse Visual System.
eNeuro
Jul 17, 2018
The mammalian visual system consists of several anatomically distinct areas, layers, and cell types. To understand the role of these subpopulations in visual information processing, we analyzed neural signals recorded from excitatory neurons from var...
Identification of 170 New Long Noncoding RNAs in .
BioMed research international
Jul 11, 2018
Long noncoding RNAs (lncRNAs) are transcripts generally longer than 200 nucleotides with no or poor protein coding potential, and most of their functions are also poorly characterized. Recently, an increasing number of studies have shown that lncRNAs...
An open-source tool for analysis and automatic identification of dendritic spines using machine learning.
PloS one
Jul 5, 2018
Synaptic plasticity, the cellular basis for learning and memory, is mediated by a complex biochemical network of signaling proteins. These proteins are compartmentalized in dendritic spines, the tiny, bulbous, post-synaptic structures found on neuron...
Catechin rich butanol fraction extracted from Acacia catechu L. (a thirst quencher) exhibits immunostimulatory potential.
Journal of food and drug analysis
Jul 2, 2018
Acacia catechu L., (Fabaceae) named as "catechu" is a plant, the decoction of heartwood of which is daily consumed as thirst quencher by a good percentage of the population in South India. The plant is mainly distributed in India and other Asian coun...
Multi-Factored Gene-Gene Proximity Measures Exploiting Biological Knowledge Extracted from Gene Ontology: Application in Gene Clustering.
IEEE/ACM transactions on computational biology and bioinformatics
Jun 21, 2018
To describe the cellular functions of proteins and genes, a potential dynamic vocabulary is Gene Ontology (GO), which comprises of three sub-ontologies namely, Biological-process, Cellular-component, and Molecular-function. It has several application...
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