AIMC Topic: Mice

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Deep Learning-Based Annotation Transfer between Molecular Imaging Modalities: An Automated Workflow for Multimodal Data Integration.

Analytical chemistry Feb 3, 2021
An ever-increasing array of imaging technologies are being used in the study of complex biological samples, each of which provides complementary, occasionally overlapping information at different length scales and spatial resolutions. It is important...
Molecular Imaging Histological Techniques Mice Workflow Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Animals Deep Learning
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Reconstructing Undersampled Photoacoustic Microscopy Images Using Deep Learning.

IEEE transactions on medical imaging Feb 3, 2021
One primary technical challenge in photoacoustic microscopy (PAM) is the necessary compromise between spatial resolution and imaging speed. In this study, we propose a novel application of deep learning principles to reconstruct undersampled PAM imag...
Image Processing, Computer-Assisted Mice Microscopy Spectrum Analysis Neural Networks, Computer Animals Deep Learning
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Computational identification of ubiquitination sites in Arabidopsis thaliana using convolutional neural networks.

Plant molecular biology Feb 1, 2021
We developed two CNNs for predicting ubiquitination sites in Arabidopsis thaliana, demonstrated their competitive performance, analyzed amino acid physicochemical properties and the CNN structures, and predicted ubiquitination sites in Arabidopsis. A...
Humans Amino Acids Yeasts Animals Ubiquitination Mice Arabidopsis Neural Networks, Computer Computational Biology Software Proteome Protein Processing, Post-Translational
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A computational framework for optimal control of a self-adjustive neural system with activity-dependent and homeostatic plasticity.

NeuroImage Jan 30, 2021
The control of the brain system has received increasing attention in the domain of brain science. Most brain control studies have been conducted to explore the brain network's graph-theoretic properties or to produce the desired state based on neural...
Homeostasis Mice, Transgenic Neuronal Plasticity Models, Neurological Neural Networks, Computer Hippocampus Animals Mice
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DeepLabStream enables closed-loop behavioral experiments using deep learning-based markerless, real-time posture detection.

Communications biology Jan 29, 2021
In general, animal behavior can be described as the neuronal-driven sequence of reoccurring postures through time. Most of the available current technologies focus on offline pose estimation with high spatiotemporal resolution. However, to correlate ...
Deep Learning Time Factors Image Processing, Computer-Assisted Mice, Inbred C57BL Light Conditioning, Classical Behavior, Animal Photic Stimulation Odorants Animals Mice Olfactory Perception Head Movements Posture Thalamus Video Recording Optogenetics Smell
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Machine learning approaches reveal subtle differences in breathing and sleep fragmentation in -derived astrocytes ablated mice.

Journal of neurophysiology Jan 27, 2021
Modern neurophysiology research requires the interrogation of high-dimensionality data sets. Machine learning and artificial intelligence (ML/AI) workflows have permeated into nearly all aspects of daily life in the developed world but have not been ...
Sleep Respiration Homeodomain Proteins Plethysmography Neurophysiology Astrocytes Electroencephalography Workflow Mice Genotype Transcription Factors Animals Gene Expression Profiling Machine Learning
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Integrated functional neuronal network analysis of 3D silk-collagen scaffold-based mouse cortical culture.

STAR protocols Jan 25, 2021
Bioengineered 3D tunable neuronal constructs are a versatile platform for studying neuronal network functions, offering numerous advantages over existing technologies and providing for the discovery of new biological insights. Functional neural netwo...
Silk Nerve Net Neurons Neural Networks, Computer Animals Collagen Tissue Scaffolds Mice Cerebral Cortex Cell Differentiation Cell Culture Techniques
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Manipulation of Single Neural Stem Cells and Neurons in Brain Slices using Robotic Microinjection.

Journal of visualized experiments : JoVE Jan 21, 2021
A central question in developmental neurobiology is how neural stem and progenitor cells form the brain. To answer this question, one needs to label, manipulate, and follow single cells in the brain tissue with high resolution over time. This task is...
Neurons Mice Neural Stem Cells Automation Tissue Culture Techniques Brain Mice, Inbred C57BL Fluorescent Antibody Technique Microinjections Animals Robotics Single-Cell Analysis
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Automatic classification of mice vocalizations using Machine Learning techniques and Convolutional Neural Networks.

PloS one Jan 19, 2021
Ultrasonic vocalizations (USVs) analysis is a well-recognized tool to investigate animal communication. It can be used for behavioral phenotyping of murine models of different disorders. The USVs are usually recorded with a microphone sensitive to ul...
Ultrasonic Waves Ultrasonics Animal Communication Animals Mice Support Vector Machine Vocalization, Animal Neural Networks, Computer Machine Learning
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DeepLPI: a multimodal deep learning method for predicting the interactions between lncRNAs and protein isoforms.

BMC bioinformatics Jan 18, 2021
BACKGROUND: Long non-coding RNAs (lncRNAs) regulate diverse biological processes via interactions with proteins. Since the experimental methods to identify these interactions are expensive and time-consuming, many computational methods have been prop...
Deep Learning Mice Computational Biology RNA, Long Noncoding Neural Networks, Computer Animals Protein Isoforms
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