Antimicrobial resistance (AMR) in enterica serotype Kentucky ( Kentucky) is a global challenge, with increasing resistance to cephalosporins, ciprofloxacin, and carbapenems significantly limiting treatment strategies, yet its worldwide dissemination...
Antimicrobial agents and chemotherapy
Oct 31, 2025
While associations of antibiotic resistance traits are not random in multidrug-resistant (MDR) bacteria, clinically relevant resistance patterns remain underexplored. This study used association-set mining to explore resistance associations within i...
European journal of medicinal chemistry
Oct 16, 2025
Staphylococcus aureus (S. aureus) is one of the most concerned Gram-positive bacteria due to its resistance to the commonly used antibiotics, methicillin. To address the threat of methicillin-resistant S. aureus (MRSA), new classes of antibiotics are...
Deep learning models show promise in accelerating the design and optimization of antimicrobial peptides (AMPs), but current methods face challenges, such as low success rates, or large virtual library scales. In this study, we introduce DLFea4AMPGen,...
It is essential to eliminate harmful microbes from vital aspects of our lives, including dental instruments and other healthcare devices, cosmetics, foods, and products that come into contact with them. Electrical stimulation (ES) has been proposed t...
The emergence of multidrug-resistant pathogens has increased the urgency for alternative treatment options for infections like cystitis. This study focused on the green synthesis of silver nanoparticles and cysteine-conjugated silver nanoparticles ut...
Extended-spectrum β-lactamases in Escherichia coli poses a significant threat for clinicians in tertiary healthcare settings, rendering treatments ineffective with newer β-lactam-β-lactamase inhibitors combinations. To overcome this, the present stud...
UNLABELLED: Bloodstream infections (BSIs) have become increasingly challenging to treat due to emerging antimicrobial resistance (AMR). As rapid administration of appropriate antimicrobials is crucial to positive patient outcomes, clinical alternativ...
Journal of chemical information and modeling
Sep 17, 2025
The escalating issue of antibiotic resistance has created an urgent global demand within the biomedical field for the discovery of novel antimicrobial molecules as alternatives to traditional antibiotics. Previous studies have reported the identifica...
Phytomedicine : international journal of phytotherapy and phytopharmacology
Sep 15, 2025
INTRODUCTION: The global rise of antimicrobial resistance (AMR), particularly among biofilm-forming bacteria and fungi, has created an urgent need for novel therapeutics. Nordihydroguaiaretic acid (NDGA), a plant-derived polyphenolic lignan, has demo...
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