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JPMA. The Journal of the Pakistan Medical Association
Jun 1, 2024
Liquid biopsy has multiple benefits and is used extensively in other fields of oncology, but its role in neuro-oncology has been limited so far. Multiple tumour-derived materials like circulating tumour cells (CTCs), tumour-educated platelets (TEPs),...
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences
Apr 25, 2024
MiRNAs are a class of small non-coding RNAs, which regulate gene expression post-transcriptionally by partial complementary base pairing. Aberrant miRNA expressions have been reported in tumor tissues and peripheral blood of cancer patients. In recen...
Frontiers in bioscience (Landmark edition)
Jan 12, 2024
BACKGROUND: The current standard for Parkinson's disease (PD) diagnosis is often imprecise and expensive. However, the dysregulation patterns of microRNA (miRNA) hold potential as a reliable and effective non-invasive diagnosis of PD.
Nucleic acids research
Jan 5, 2024
Biomarkers play an important role in various area such as personalized medicine, drug development, clinical care, and molecule breeding. However, existing animals' biomarker resources predominantly focus on human diseases, leaving a significant gap i...
Briefings in bioinformatics
May 19, 2023
MicroRNAs are small regulatory RNAs that decrease gene expression after transcription in various biological disciplines. In bioinformatics, identifying microRNAs and predicting their functionalities is critical. Finding motifs is one of the most well...
Briefings in bioinformatics
Mar 19, 2023
Discovering pre-microRNAs (miRNAs) is the core of miRNA discovery. Using traditional sequence/structural features, many tools have been published to discover miRNAs. However, in practical applications like genomic annotations, their actual performanc...
Briefings in bioinformatics
Mar 19, 2023
Potential miRNA-disease associations (MDA) play an important role in the discovery of complex human disease etiology. Therefore, MDA prediction is an attractive research topic in the field of biomedical machine learning. Recently, several models have...
Mathematical biosciences and engineering : MBE
Feb 7, 2023
Phasic small interfering RNAs are plant secondary small interference RNAs that typically generated by the convergence of miRNAs and polyadenylated mRNAs. A growing number of studies have shown that miRNA-initiated phasiRNA plays crucial roles in regu...
Briefings in bioinformatics
Jan 19, 2023
MicroRNA (miRNA)-target interaction (MTI) plays a substantial role in various cell activities, molecular regulations and physiological processes. Published biomedical literature is the carrier of high-confidence MTI knowledge. However, digging out th...
Frontiers in bioscience (Landmark edition)
Mar 16, 2022
This study reviews the recent progress of machine learning for the early diagnosis of thyroid disease. Based on the results of this review, different machine learning methods would be appropriate for different types of data for the early diagnosis of...