Translational vision science & technology
Jun 16, 2020
PURPOSE: To develop a neural network (NN)-based approach, with limited training resources, that identifies and counts the number of retinal pigment epithelium (RPE) cells in confocal microscopy images obtained from cell culture or mice RPE/choroid fl...
International journal of computer assisted radiology and surgery
May 15, 2020
PURPOSE: Probe-based confocal laser endomicroscopy (pCLE) enables performing an optical biopsy via a probe. pCLE probes consist of multiple optical fibres arranged in a bundle, which taken together generate signals in an irregularly sampled pattern. ...
INTRODUCTION: Brain organoids are highly complex multi-cellular tissue proxies, which have recently risen as novel tools to study neurodegenerative diseases such as Parkinson's disease (PD). However, with increasing complexity of the system, usage of...
BACKGROUND: Photographic diabetic retinopathy screening requires labour-intensive grading of retinal images by humans. Automated retinal image analysis software (ARIAS) could provide an alternative to human grading. We compare the performance of an A...
All living systems are maintained by a constant flux of metabolic energy and, among the different reactions, the process of lipids storage and lipolysis is of fundamental importance. Current research has focused on the investigation of lipid droplets...
Journal of the American Academy of Dermatology
Apr 26, 2020
Managing the balance between accurately identifying early stage melanomas while avoiding obtaining biopsy specimens of benign lesions (ie, overbiopsy) is the major challenge of melanoma detection. Decision making can be especially difficult in patien...
Medical & biological engineering & computing
Apr 21, 2020
In cell-based research, the process of visually monitoring cells generates large image datasets that need to be evaluated for quantifiable information in order to track the effectiveness of treatments in vitro. With the traditional, end-point assay-b...
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Jan 24, 2020
Barrett cancer is a treatable disease when detected at an early stage. However, current screening protocols are often not effective at finding the disease early. Volumetric Laser Endomicroscopy (VLE) is a promising new imaging tool for finding dyspla...
In this article, we address the problem of the classification of the health state of the colon's wall of mice, possibly injured by cancer with machine learning approaches. This problem is essential for translational research on cancer and is a priori...
The Journal of investigative dermatology
Dec 12, 2019
In vivo reflectance confocal microscopy (RCM) enables clinicians to examine lesions' morphological and cytological information in epidermal and dermal layers while reducing the need for biopsies. As RCM is being adopted more widely, the workflow is e...
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