AIMC Topic: Middle Aged

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Systemic inflammation mediates the relationship between urinary cadmium and chronic cough risk: findings based on multiple statistical models.

Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine
Epidemiological research examining the relationship between urinary cadmium and the risk of chronic cough remains scarce. This study included 2965 participants for a cross-sectional study from the NHANES. The weighted quantile sum (WQS) regression, b...

A deep learning model combining circulating tumor cells and radiological features in the multi-classification of mediastinal lesions in comparison with thoracic surgeons: a large-scale retrospective study.

BMC medicine
BACKGROUND: CT images and circulating tumor cells (CTCs) are indispensable for diagnosing the mediastinal lesions by providing radiological and intra-tumoral information. This study aimed to develop and validate a deep multimodal fusion network (DMFN...

Enhanced classification of tinnitus patients using EEG microstates and deep learning techniques.

Scientific reports
This study aims to deepen the understanding and classification of tinnitus through a comprehensive analysis of EEG signals utilizing innovative microstate analysis techniques and cutting-edge machine learning approaches. EEG data were collected from ...

Machine learning model for differentiating malignant from benign thyroid nodules based on the thyroid function data.

BMJ open
OBJECTIVES: To develop and validate a machine learning (ML) model to differentiate malignant from benign thyroid nodules (TNs) based on the routine data and provide diagnostic assistance for medical professionals.

Construction of exosome non-coding RNA feature for non-invasive, early detection of gastric cancer patients by machine learning: a multi-cohort study.

Gut
BACKGROUND AND OBJECTIVE: Gastric cancer (GC) remains a prevalent and preventable disease, yet accurate early diagnostic methods are lacking. Exosome non-coding RNAs (ncRNAs), a type of liquid biopsy, have emerged as promising diagnostic biomarkers f...

Optimizing Strategy for Lung Cancer Screening: From Risk Prediction to Clinical Decision Support.

JCO clinical cancer informatics
PURPOSE: Low-dose computed tomography (LDCT) screening is effective in reducing lung cancer mortality by detecting the disease at earlier, more treatable stages. However, high false-positive rates and the associated risks of subsequent invasive diagn...

Annotation-Free Whole-Slide Image Analysis Method to Assess Immune Infiltration in Colorectal Cancer.

JCO precision oncology
PURPOSE: Tumor-infiltrating lymphocytes (TILs) play a crucial role in host antitumor processes. High level of TILs is associated with better outcomes for patients. We aim to automatically quantify TILs without any nuclei annotation and further constr...

Unsupervised Test-Time Adaptation for Hepatic Steatosis Grading Using Ultrasound B-Mode Images.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control
Ultrasound (US) is considered a key modality for the clinical assessment of hepatic steatosis (i.e., fatty liver) due to its noninvasiveness and availability. Deep learning methods have attracted considerable interest in this field, as they are capab...

Explainable Machine Learning Models for Colorectal Cancer Prediction Using Clinical Laboratory Data.

Cancer control : journal of the Moffitt Cancer Center
IntroductionEarly diagnosis of colorectal cancer (CRC) poses a significant clinical challenge. This study aims to develop machine learning (ML) models for CRC risk prediction using clinical laboratory data.MethodsThis retrospective, single-center stu...

Machine Learning Models Can Predict Tinnitus and Noise-Induced Hearing Loss.

Ear and hearing
OBJECTIVES: Despite the extensive use of machine learning (ML) models in health sciences for outcome prediction and condition classification, their application in differentiating various types of auditory disorders remains limited. This study aimed t...