AIMC Topic: Middle Aged

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Home detection of freezing of gait using support vector machines through a single waist-worn triaxial accelerometer.

PloS one
Among Parkinson's disease (PD) symptoms, freezing of gait (FoG) is one of the most debilitating. To assess FoG, current clinical practice mostly employs repeated evaluations over weeks and months based on questionnaires, which may not accurately map ...

Machine Learning Principles Can Improve Hip Fracture Prediction.

Calcified tissue international
Apply machine learning principles to predict hip fractures and estimate predictor importance in Dual-energy X-ray absorptiometry (DXA)-scanned men and women. Dual-energy X-ray absorptiometry data from two Danish regions between 1996 and 2006 were com...

Robotic-assisted gait training in Parkinson's disease: a three-month follow-up randomized clinical trial.

The International journal of neuroscience
PURPOSE: The aim of this study was to evaluate the efficacy of a robotic-assisted gait training (RAGT), together with a conventional exercise program (CEP), to improve PD ambulation, as compared to standard gait training.

Learning Effective Treatment Pathways for Type-2 Diabetes from a clinical data warehouse.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Treatment guidelines for management of type-2 diabetes mellitus (T2DM) are controversial because existing evidence from randomized clinical trials do not address many important clinical questions. Data from Electronic Medical Records (EMRs) has been ...

Predicting Prolonged Stay in the ICU Attributable to Bleeding in Patients Offered Plasma Transfusion.

AMIA ... Annual Symposium proceedings. AMIA Symposium
In blood transfusion studies, plasma transfusion (PPT) and bleeding are known to be associated with risk of prolonged ICU length of stay (ICU-LOS). However, as patients can show significant heterogeneity in response to a treatment, there might exists...

Performance analysis of a machine learning flagging system used to identify a group of individuals at a high risk for colorectal cancer.

PloS one
Individuals with colorectal cancer (CRC) have a tendency to intestinal bleeding which may result in mild to severe iron deficiency anemia, but for many colon cancer patients hematological abnormalities are subtle. The fecal occult blood test (FOBT) i...

Machine learning based compartment models with permeability for white matter microstructure imaging.

NeuroImage
Some microstructure parameters, such as permeability, remain elusive because mathematical models that express their relationship to the MR signal accurately are intractable. Here, we propose to use computational models learned from simulations to est...

Application of Machine-Learning Models to Predict Tacrolimus Stable Dose in Renal Transplant Recipients.

Scientific reports
Tacrolimus has a narrow therapeutic window and considerable variability in clinical use. Our goal was to compare the performance of multiple linear regression (MLR) and eight machine learning techniques in pharmacogenetic algorithm-based prediction o...