RATIONALE AND OBJECTIVES: Accurate determination of human epidermal growth factor receptor 2 (HER2) expression is critical for guiding targeted therapy in breast cancer. This study aimed to develop and validate a deep learning (DL)-based decision-mak...
The international journal of cardiovascular imaging
Mar 10, 2025
Invasive coronary physiology is underused and carries risks/costs. Artificial Intelligence (AI) might enable non-invasive physiology from invasive coronary angiography (CAG), possibly outperforming humans, but has seldom been explored, especially for...
BACKGROUND: Dementia is a multifaceted disorder that affects cognitive function, necessitating accurate diagnosis for effective management and treatment. Although the Mini-Mental State Examination (MMSE) is widely used to assess cognitive impairment,...
Cancer imaging : the official publication of the International Cancer Imaging Society
Mar 10, 2025
BACKGROUND: To construct and assess a deep learning (DL) signature that employs computed tomography imaging to predict the expression status of programmed cell death ligand 1 in patients with bladder cancer (BCa).
BACKGROUND: Traditional surgical education is based on observation and assistance in surgical practice. Recently introduced deep learning (DL) techniques enable the recognition of the surgical view and automatic identification of surgical landmarks. ...
BACKGROUND: Genome-wide association studies (GWAS) have identified common variants associated with metabolic dysfunction-associated steatotic liver disease (MASLD). However, rare coding variant studies have been limited by phenotyping challenges and ...
BACKGROUND: The presence of tumour-infiltrating lymphocytes (TILs) is a well-established prognostic biomarker across multiple cancer types, with higher TIL counts being associated with lower recurrence rates and improved patient survival. We aimed to...
BACKGROUND: Cognitive behavioral therapy (CBT) is a highly effective treatment for depression and anxiety disorders. Nonetheless, a substantial proportion of patients do not respond to treatment. The lack of engagement with therapeutic materials and ...
. Risk stratification of hypertension plays a crucial role in the treatment decisions and medication guidance during clinical practices. Although fruitful achievements have been reported on risk stratification of hypertension, the potential use of am...
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
Mar 9, 2025
BACKGROUND: Severe asthma presents a major challenge to health care and negatively affects the quality of life of patients. Understanding the factors predicting the development of severe asthma is limited.
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