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Development and validation of a predictive machine learning model for postoperative long-term diabetes insipidus following transsphenoidal surgery for sellar lesions.

Clinical neurology and neurosurgery
OBJECTIVE: Diabetes Insipidus (DI) is a common complication that occurs following transsphenoidal surgery for sellar lesions. DI is usually transient but can be permanent in select patients. Prior studies have described preoperative risk factors for ...

Enhanced non-invasive machine learning approach for early colorectal cancer detection: Predictive modeling and validation in a Jordanian cohort.

Computers in biology and medicine
BACKGROUND: Colorectal cancer (CRC) ranks as the third most prevalent cancer worldwide, posing significant public health challenges. Late-stage detection often results in poor treatment outcomes, elevating mortality rates. The economic and psychologi...

Classification of Grades of Subchondral Sclerosis from Knee Radiographic Images Using Artificial Intelligence.

Sensors (Basel, Switzerland)
Osteoarthritis (OA) is the most common joint disease, affecting over 300 million people worldwide. Subchondral sclerosis is a key indicator of OA. Currently, the diagnosis of subchondral sclerosis is primarily based on radiographic images; however, r...

Deep Learning-Driven Abbreviated Shoulder MRI Protocols: Diagnostic Accuracy in Clinical Practice.

Tomography (Ann Arbor, Mich.)
BACKGROUND: Deep learning (DL) reconstruction techniques have shown promise in reducing MRI acquisition times while maintaining image quality. However, the impact of different acceleration factors on diagnostic accuracy in shoulder MRI remains unexpl...

Molecular features and diagnostic modeling of synovium- and IPFP-derived OA macrophages in the inflammatory microenvironment via scRNA-seq and machine learning.

Journal of orthopaedic surgery and research
BACKGROUND: Osteoarthritis (OA) is the leading cause of degenerative joint disease, with total joint replacement as the only definitive cure. However, no disease-modifying therapy is currently available. Inflammation and fibrosis in the infrapatellar...

Predicting depression and unravelling its heterogeneous influences in middle-aged and older people populations: a machine learning approach.

BMC psychology
BACKGROUND: Aging has become a global trend, and depression, as an accompanying issue, poses a significant threat to the health of middle-aged and older adults. Existing studies primarily rely on statistical methods such as logistic regression for sm...

Automated machine learning for early prediction of systemic inflammatory response syndrome in acute pancreatitis.

BMC medical informatics and decision making
BACKGROUND: Systemic inflammatory response syndrome (SIRS) is a frequent and serious complication of acute pancreatitis (AP), often associated with increased mortality. This study aims to leverage automated machine learning (AutoML) algorithms to cre...

Predicting coronary heart disease with advanced machine learning classifiers for improved cardiovascular risk assessment.

Scientific reports
Worldwide, coronary heart disease (CHD) is a leading cause of mortality, and its early prediction remains a critical challenge in clinical data analysis. Machine learning (ML) offers valuable diagnostic support by leveraging healthcare data to enhanc...

Automated opportunistic screening for osteoporosis using deep learning-based automatic segmentation and radiomics on proximal femur images from low-dose abdominal CT.

BMC musculoskeletal disorders
RATIONALE AND OBJECTIVES: To establish an automated osteoporosis detection model based on low-dose abdominal CT (LDCT). This model combined a deep learning-based automatic segmentation of the proximal femur with a radiomics-based bone status classifi...

Sensitivity of a deep-learning-based breast cancer risk prediction model.

Physics in medicine and biology
When it comes to the implementation of deep-learning based breast cancer risk (BCR) prediction models in clinical settings, it is important to be aware that these models could be sensitive to various factors, especially those arising from the acquisi...