AIMC Topic: Models, Animal

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Evaluation of a CT-Guided Robotic System for Precise Percutaneous Needle Insertion.

Journal of vascular and interventional radiology : JVIR
PURPOSE: To assess overall targeting accuracy for CT-guided needle insertion using prototype robotic system for common target sites.

Design and validation of an ontology-driven animal-free testing strategy for developmental neurotoxicity testing.

Toxicology and applied pharmacology
Developmental neurotoxicity entails one of the most complex areas in toxicology. Animal studies provide only limited information as to human relevance. A multitude of alternative models have been developed over the years, providing insights into mech...

Current status of endovascular catheter robotics.

The Journal of cardiovascular surgery
In this review, we will detail the evolution of endovascular therapy as the basis for the development of catheter-based robotics. In parallel, we will outline the evolution of robotics in the surgical space and how the convergence of technology and t...

[In vitro Modulating Activity of aqueous extracts from American Plants on Chlorpyrifos-induced toxicity on Murine Splenocytes].

Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina)
BACKGROUND: Chlorpyrifos is an highly toxic pesticide, which can induce immunotoxicity with deleterious effects on health worldwide. On the other hand, American plants can provide derivatives with protective and immunostimulating activity. Thus, plan...

Dynamical analysis and development of a biologically inspired SMA caterpillar robot.

Bioinspiration & biomimetics
With the goal of robustly designing and fabricating a soft robot based on a caterpillar featuring shape memory alloy (SMA) actuators, analytical and numerical models for a soft robot were created based on the forward crawling motion of the Manduca se...

From biokinematics to a robotic active vision system.

Bioinspiration & biomimetics
Barn owls move their heads in very particular motions, compensating for the quasi-immovability of their eyes. These efficient predators often perform peering side-to-side head motions when scanning their surroundings and seeking prey. In this work, w...

A robot for high yield electrophysiology and morphology of single neurons in vivo.

Nature communications
Single-cell characterization and perturbation of neurons provides knowledge critical to addressing fundamental neuroscience questions including the structure-function relationship and neuronal cell-type classification. Here we report a robot for effi...

An unsupervised learning approach for tracking mice in an enclosed area.

BMC bioinformatics
BACKGROUND: In neuroscience research, mouse models are valuable tools to understand the genetic mechanisms that advance evidence-based discovery. In this context, large-scale studies emphasize the need for automated high-throughput systems providing ...

A cable-driven soft robot surgical system for cardiothoracic endoscopic surgery: preclinical tests in animals.

Surgical endoscopy
BACKGROUND: Minimally invasive surgery attracts more and more attention because of the advantages of minimal trauma, less bleeding and pain and low complication rate. However, minimally invasive surgery for beating hearts is still a challenge. Our go...

Classification of Porcine Cranial Fracture Patterns Using a Fracture Printing Interface.

Journal of forensic sciences
Distinguishing between accidental and abusive head trauma in children can be difficult, as there is a lack of baseline data for pediatric cranial fracture patterns. A porcine head model has recently been developed and utilized in a series of studies ...