AIMC Topic: Multicenter Studies as Topic

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Evaluation of visual patient predictive for enhancing level 3 situation awareness: protocol for a multicentre randomised computer-based simulation and diagnostic accuracy study (true positive rate, precision, average lead time).

BMJ open
INTRODUCTION: Visual Patient Predictive (VPP) is an AI-based extension of the Visual Patient Avatar (VPA) that integrates deep learning models to predict upcoming vital sign deviations and display them as dashed visual elements. By explicitly showing...

Predictive modelling of clinically significant depressive symptoms after coronary artery bypass graft surgery: protocol for a multicentre observational study in two Swiss hospitals (the PsyCor study).

BMJ open
INTRODUCTION: Coronary artery bypass grafting (CABG) remains one of the most commonly performed cardiac surgeries worldwide. Despite surgical advancements, a significant proportion of patients experience psychological distress following surgery, with...

Development and validation of a diagnostic prediction model for pancreatic ductal adenocarcinoma: VAPOR 1, protocol for a prospective multicentre case-control study.

BMJ open
INTRODUCTION: Pancreatic ductal adenocarcinoma (PDAC) continues to have extremely poor patient outcomes, unlike other cancer types which have seen significant improvements in their treatments and survival. A major contributing factor is that PDAC is ...

Non-invasive breath testing to detect colorectal cancer: protocol for a multicentre, case-control development and validation study (COBRA2 study).

BMC cancer
BACKGROUND: Colorectal cancer (CRC) is the fourth most common cancer in the United Kingdom. The five-year survival rate from CRC is only 10% when discovered at a late stage, but can exceed 90% if diagnosed early. Symptoms related to CRC can be non-sp...

Curating a knowledge base for patients with neurosyphilis: a study protocol of a DEep learning Framework for pErsonalized prediction of Adverse prognosTic events in NeuroSyphilis (DEFEAT-NS).

BMJ open
INTRODUCTION: Adverse prognostic events (APE) of neurosyphilis include ongoing syphilitic meningitis, meningovascular syphilis, parenchymatous neurosyphilis and death. Its complexity and rarity have the potential to result in the underestimated true ...

Imaging analysis using Artificial Intelligence to predict outcomes after endovascular aortic aneurysm repair: protocol for a retrospective cohort study.

BMJ open
INTRODUCTION: Endovascular aortic aneurysm repair (EVAR) requires long-term surveillance to detect and treat postoperative complications. However, prediction models to optimise follow-up strategies are still lacking. The primary objective of this stu...

PREACT-digital: study protocol for a longitudinal, observational multicentre study on digital phenotypes of non-response to cognitive behavioural therapy for internalising disorders.

BMJ open
INTRODUCTION: Cognitive behavioural therapy (CBT) serves as a first-line treatment for internalising disorders (ID), encompassing depressive, anxiety or obsessive-compulsive disorders. Nonetheless, a substantial proportion of patients do not experien...