AIMC Topic: Nanoparticles
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Deep Learning for the Accurate Prediction of Triggered Drug Delivery.
IEEE transactions on nanobioscience
Jan 2, 2025
The need to mitigate the adverse effects of chemotherapy has driven the exploration of innovative drug delivery approaches. One emerging trend in cancer treatment is the utilization of Drug Delivery Systems (DDSs), facilitated by nanotechnology. Nano...
Efficient and stable extraction of nano-sized plastic particles enabled by bio-inspired magnetic "robots" in water.
Environmental pollution (Barking, Essex : 1987)
Dec 31, 2024
In this research, a rationally-designed strategy was employed to address the crucial issue of removing nano-plastics (NPs) from aquatic environments, which was based on fabricating sea urchin-like structures of FeO magnetic robots (MagRobots). Throug...
Antibacterial effects of thyme oil loaded solid lipid and chitosan nano-carriers against Salmonella Typhimurium and Escherichia coli as food preservatives.
PloS one
Dec 31, 2024
OBJECTIVES: Escherichia coli and Salmonella Typhimurium are frequent causes of foodborne illness affecting many people annually. In order to develop natural antimicrobial agents against these microorganisms, thyme oil (TO) was considered as active an...
Development of hybrid bionanocomposites of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) with zinc oxide and silicon-doped hydroxyapatite nanocrystals and machine learning for predicting dynamic mechanical properties.
International journal of biological macromolecules
Dec 30, 2024
The development of hybrid materials that integrate bioactive and antimicrobial properties within a biodegradable and biocompatible polymer matrix is a key focus in current biomedical research and applications. A significant research gap exists in the...
Artificial intelligence-driven rational design of ionizable lipids for mRNA delivery.
Nature communications
Dec 30, 2024
Lipid nanoparticles (LNPs) have proven effective in mRNA delivery, as evidenced by COVID-19 vaccines. Its key ingredient, ionizable lipids, is traditionally optimized by inefficient and costly experimental screening. This study leverages artificial i...
CXCL12 impact on glioblastoma cells behaviors under dynamic culture conditions: Insights for developing new therapeutic approaches.
PloS one
Dec 23, 2024
Glioblastoma multiforme (GBM) is the most prevalent malignant brain tumor, with an average survival time of 14 to 20 months. Its capacity to invade brain parenchyma leads to the failure of conventional treatments and subsequent tumor recurrence. Rece...
3D electron microscopy for analyzing nanoparticles in the tumor endothelium.
Proceedings of the National Academy of Sciences of the United States of America
Dec 12, 2024
Delivering medical agents to diseased tissues has been challenging, leading researchers to study the in vivo transport process in the body for improving delivery. Many imaging techniques exist for mapping the distribution of medical agent-carrying na...
Extending visual range of bacteria with upconversion nanoparticles and constructing NIR-responsive bio-microrobots.
Journal of colloid and interface science
Dec 1, 2024
The motility of bacteria is crucial for navigating competitive environments and is closely linked to physiological activities essential for their survival, such as biofilm development. Precise regulation of bacterial motility enhances our understandi...
Machine learning strengthened formulation design of pharmaceutical suspensions.
International journal of pharmaceutics
Nov 19, 2024
Many different formulation strategies have been investigated to oppose suboptimal treatment of long-term or chronic conditions, one of which are the nano- and microsuspensions prepared as long-acting injectables to prolong the release of an active ph...
A Divide-and-Conquer Approach to Nanoparticle Global Optimisation Using Machine Learning.
Journal of chemical information and modeling
Nov 15, 2024
Global optimization of the structure of atomic nanoparticles is often hampered by the presence of many funnels on the potential energy surface. While broad funnels are readily encountered and easily exploited by the search, narrow funnels are more di...
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