AIMC Topic: Neural Pathways
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Brain-wide input-output analysis of tuberal nucleus somatostatin neurons reveals hierarchical circuits for orchestrating feeding behavior.
Nature communications
Jul 1, 2025
Feeding is an innate behavior critical for survival but is also influenced by many non-nutritional factors such as emotion, social context and environmental conditions. Recently, tuberal nucleus somatostatin (SST) neurons have been identified as a ke...
Functional connectome-based predictive modeling of suicidal ideation.
Journal of affective disorders
May 27, 2025
Suicide represents an egregious threat to society despite major advancements in medicine, in part due to limited knowledge of the biological mechanisms of suicidal behavior. We apply a connectome predictive modeling machine learning approach to ident...
From resting-state functional hippocampal centrality to functional outcome: An extended neurocognitive model of psychosis.
Psychiatry research
May 16, 2025
BACKGROUND: We previously proposed a neurocognitive model of psychosis in which reduced morphometric hippocampal-cortical connectivity precedes impaired episodic memory, social cognition, negative symptoms, and functional outcome. We provided support...
Cortical-subcortical neural networks for motor learning and storing sequence memory.
Neural networks : the official journal of the International Neural Network Society
May 7, 2025
Motor sequence learning relies on the synergistic collaboration of multiple brain regions. However, most existing models for motor sequence learning primarily focus on functional-level analyses of sequence memory mechanisms, providing limited neuroph...
Brain circuits that regulate social behavior.
Molecular psychiatry
Apr 26, 2025
Social interactions are essential for the survival of individuals and the reproduction of populations. Social stressors, such as social defeat and isolation, can lead to emotional disorders and cognitive impairments. Furthermore, dysfunctional social...
Altered static and dynamic functional network connectivity and combined Machine learning in asthma.
Neuroscience
Apr 26, 2025
Asthma is a reversible disease characterized by airflow limitation and chronic airway inflammation. Previous neuroimaging studies have shown structural and functional abnormalities in the brains of individuals with asthma. However, earlier research h...
Associations among white matter microstructural changes and the development of emotional reactivity and regulation in infancy.
Molecular psychiatry
Apr 23, 2025
Deficits in emotional reactivity and regulation assessed in infancy, including high levels of negative emotionality (NE), low positive emotionality (PE) and low soothability, can predict future affective and behavioral disorders. White matter (WM) tr...
Alterations in static and dynamic functional network connectivity in chronic low back pain: a resting-state network functional connectivity and machine learning study.
Neuroreport
Apr 9, 2025
Low back pain (LBP) is a prevalent pain condition whose persistence can lead to changes in the brain regions responsible for sensory, cognitive, attentional, and emotional processing. Previous neuroimaging studies have identified various structural a...
Comparative analysis of functional network dynamics in high and low alcohol preference mice.
Experimental neurology
Apr 4, 2025
Individual variability preference is a typical characteristic of alcohol drinking behaviors, with a higher risk for the development of alcohol use disorders (AUDs) in high alcohol preference (HP) populations. Here, we created a map of alcohol-related...
Sparse connectivity enables efficient information processing in cortex-like artificial neural networks.
Frontiers in neural circuits
Mar 13, 2025
Neurons in cortical networks are very sparsely connected; even neurons whose axons and dendrites overlap are highly unlikely to form a synaptic connection. What is the relevance of such sparse connectivity for a network's function? Surprisingly, it h...
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