AIMC Topic: Neuronal Plasticity

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Neuroplasticity-Based Technologies and Interventions for Restoring Motor Functions in Multiple Sclerosis.

Advances in experimental medicine and biology
Motor impairments are very common in multiple sclerosis (MS), leading to a reduced Quality of Life and active participation. In the past decades, new insights into the functional reorganization processes that occur after a brain injury have been intr...

Understanding the role of astrocytic GABA in simulated neural networks.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Astrocytes actively influence the behavior of the surrounding neuronal network including changes of the synaptic plasticity and neuronal excitability. These dynamics are altered in diseases like Alzheimer's, where the release of the gliotransmitter G...

Combining Dopaminergic Facilitation with Robot-Assisted Upper Limb Therapy in Stroke Survivors: A Focused Review.

American journal of physical medicine & rehabilitation
Despite aggressive conventional therapy, lasting hemiplegia persists in a large percentage of stroke survivors. The aim of this article is to critically review the rationale behind targeting multiple sites along the motor learning network by combinin...

Synaptic Mechanisms of Memory Consolidation during Sleep Slow Oscillations.

The Journal of neuroscience : the official journal of the Society for Neuroscience
UNLABELLED: Sleep is critical for regulation of synaptic efficacy, memories, and learning. However, the underlying mechanisms of how sleep rhythms contribute to consolidating memories acquired during wakefulness remain unclear. Here we studied the ro...

Homeostatic Activity-Dependent Tuning of Recurrent Networks for Robust Propagation of Activity.

The Journal of neuroscience : the official journal of the Society for Neuroscience
UNLABELLED: Developing neuronal networks display spontaneous bursts of action potentials that are necessary for circuit organization and tuning. While spontaneous activity has been shown to instruct map formation in sensory circuits, it is unknown wh...

Electroencephalographic markers of robot-aided therapy in stroke patients for the evaluation of upper limb rehabilitation.

International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation
Stroke is the leading cause of permanent disability in developed countries; its effects may include sensory, motor, and cognitive impairment as well as a reduced ability to perform self-care and participate in social and community activities. A numbe...

A Simple Network Architecture Accounts for Diverse Reward Time Responses in Primary Visual Cortex.

The Journal of neuroscience : the official journal of the Society for Neuroscience
UNLABELLED: Many actions performed by animals and humans depend on an ability to learn, estimate, and produce temporal intervals of behavioral relevance. Exemplifying such learning of cued expectancies is the observation of reward-timing activity in ...

Trunk robot rehabilitation training with active stepping reorganizes and enriches trunk motor cortex representations in spinal transected rats.

The Journal of neuroscience : the official journal of the Society for Neuroscience
Trunk motor control is crucial for postural stability and propulsion after low thoracic spinal cord injury (SCI) in animals and humans. Robotic rehabilitation aimed at trunk shows promise in SCI animal models and patients. However, little is known ab...

Do post-stroke patients benefit from robotic verticalization? A pilot-study focusing on a novel neurophysiological approach.

Restorative neurology and neuroscience
BACKGROUND: Tilt-table equipped with the dynamic foot-support (ERIGO) and the functional electric stimulation could be a safe and suitable device for stabilization of vital signs, increasing patient's motivation for further recovery, decreasing the d...