AIMC Topic: Observer Variation

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Comparing machine and human reviewers to evaluate the risk of bias in randomized controlled trials.

Research synthesis methods
BACKGROUND: Evidence from new health technologies is growing, along with demands for evidence to inform policy decisions, creating challenges in completing health technology assessments (HTAs)/systematic reviews (SRs) in a timely manner. Software can...

Improved Accuracy in Optical Diagnosis of Colorectal Polyps Using Convolutional Neural Networks with Visual Explanations.

Gastroenterology
BACKGROUND & AIMS: Narrow-band imaging (NBI) can be used to determine whether colorectal polyps are adenomatous or hyperplastic. We investigated whether an artificial intelligence (AI) system can increase the accuracy of characterizations of polyps b...

Automated segmentation of the left ventricle from MR cine imaging based on deep learning architecture.

Biomedical physics & engineering express
BACKGROUND: Magnetic resonance cine imaging is the accepted standard for cardiac functional assessment. Left ventricular (LV) segmentation plays a key role in volumetric functional quantification of the heart. Conventional manual analysis is time-con...

Changes in cancer detection and false-positive recall in mammography using artificial intelligence: a retrospective, multireader study.

The Lancet. Digital health
BACKGROUND: Mammography is the current standard for breast cancer screening. This study aimed to develop an artificial intelligence (AI) algorithm for diagnosis of breast cancer in mammography, and explore whether it could benefit radiologists by imp...

Observer-independent assessment of psoriasis-affected area using machine learning.

Journal of the European Academy of Dermatology and Venereology : JEADV
BACKGROUND: Assessment of psoriasis severity is strongly observer-dependent, and objective assessment tools are largely missing. The increasing number of patients receiving highly expensive therapies that are reimbursed only for moderate-to-severe ps...

Effect of a deep-learning computer-aided detection system on adenoma detection during colonoscopy (CADe-DB trial): a double-blind randomised study.

The lancet. Gastroenterology & hepatology
BACKGROUND: Colonoscopy with computer-aided detection (CADe) has been shown in non-blinded trials to improve detection of colon polyps and adenomas by providing visual alarms during the procedure. We aimed to assess the effectiveness of a CADe system...

Automated deep-learning system for Gleason grading of prostate cancer using biopsies: a diagnostic study.

The Lancet. Oncology
BACKGROUND: The Gleason score is the strongest correlating predictor of recurrence for prostate cancer, but has substantial inter-observer variability, limiting its usefulness for individual patients. Specialised urological pathologists have greater ...

Segmentation of organs-at-risk in cervical cancer CT images with a convolutional neural network.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: We introduced and evaluated an end-to-end organs-at-risk (OARs) segmentation model that can provide accurate and consistent OARs segmentation results in much less time.

Assessment of individual tumor buds using keratin immunohistochemistry: moderate interobserver agreement suggests a role for machine learning.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Tumor budding is a promising and cost-effective biomarker with strong prognostic value in colorectal cancer. However, challenges related to interobserver variability persist. Such variability may be reduced by immunohistochemistry and computer-aided ...