AIMC Topic: Osteoarthritis, Knee

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An expert system feedback tool improves the reliability of clinical gait kinematics for older adults with lower limb osteoarthritis.

Gait & posture
Recently, an expert system was developed to provide feedback to examiners with the aim of improving reliability of marker-based gait analysis. The purpose of the current study was to evaluate the effectiveness of this novel feedback tool in improving...

Predicting early symptomatic osteoarthritis in the human knee using machine learning classification of magnetic resonance images from the osteoarthritis initiative.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society
UNLABELLED: The purpose of this study is to evaluate the ability of a machine learning algorithm to classify in vivo magnetic resonance images (MRI) of human articular cartilage for development of osteoarthritis (OA). Sixty-eight subjects were select...

Detecting knee osteoarthritis and its discriminating parameters using random forests.

Medical engineering & physics
This paper tackles the problem of automatic detection of knee osteoarthritis. A computer system is built that takes as input the body kinetics and produces as output not only an estimation of presence of the knee osteoarthritis, as previously done in...

Tenascin-C Prevents Articular Cartilage Degeneration in Murine Osteoarthritis Models.

Cartilage
Objective The objective of this study was to determine whether intra-articular injections of tenascin-C (TNC) could prevent cartilage damage in murine models of osteoarthritis (OA). Design Fluorescently labeled TNC was injected into knee joints and i...

Hyaluronic Acid Versus Platelet-Rich Plasma: A Prospective, Double-Blind Randomized Controlled Trial Comparing Clinical Outcomes and Effects on Intra-articular Biology for the Treatment of Knee Osteoarthritis.

The American journal of sports medicine
BACKGROUND: The use of platelet-rich plasma (PRP) for the treatment of osteoarthritis (OA) has demonstrated mixed clinical outcomes in randomized controlled trials when compared with hyaluronic acid (HA), an accepted nonsurgical treatment for symptom...

Simple Scoring System and Artificial Neural Network for Knee Osteoarthritis Risk Prediction: A Cross-Sectional Study.

PloS one
BACKGROUND: Knee osteoarthritis (OA) is the most common joint disease of adults worldwide. Since the treatments for advanced radiographic knee OA are limited, clinicians face a significant challenge of identifying patients who are at high risk of OA ...

Can Robot-Assisted Unicompartmental Knee Arthroplasty Be Cost-Effective? A Markov Decision Analysis.

The Journal of arthroplasty
BACKGROUND: Unicompartmental knee arthroplasty (UKA) is a treatment option for single-compartment knee osteoarthritis. Robotic assistance may improve survival rates of UKA, but the cost-effectiveness of robot-assisted UKA is unknown. The purpose of t...

Machine learning classification of OARSI-scored human articular cartilage using magnetic resonance imaging.

Osteoarthritis and cartilage
OBJECTIVE: The purpose of this study is to evaluate the ability of machine learning to discriminate between magnetic resonance images (MRI) of normal and pathological human articular cartilage obtained under standard clinical conditions.

Influence of Robotic Versus Manual Technology for Achieving Sagittal Targets in Total Knee Arthroplasty Using a Cruciate-Retaining and Medial-Stabilized Implant.

The Journal of arthroplasty
BACKGROUND: Most of the focus regarding total knee arthroplasty (TKA) implant positioning and alignment has been centered on the coronal plane. Posterior condylar offset (PCO) and tibial slope (TS) are sagittal parameters that are measured on radiogr...