AIMC Topic: Ovarian Neoplasms

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Integrating bulk RNA-seq and scRNA-seq analyses with machine learning to predict platinum response and prognosis in ovarian cancer.

Scientific reports
Platinum-based therapy is an integral part of the standard treatment for ovarian cancer. However, despite extensive research spanning several decades, the identification of dependable predictive biomarkers for platinum response in clinical practice h...

[WW domain-containing ubiquitin E3 ligase 1 regulates immune infiltration in tumor microenvironment of ovarian cancer].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University
OBJECTIVES: To explore the association of the expression of WW domain-containing ubiquitin E3 ligase 1 (WWP1) with immune infiltration in tumor microenvironment (TME) of ovarian cancer.

A Deep-Learning Framework for Ovarian Cancer Subtype Classification Using Whole Slide Images.

Studies in health technology and informatics
Ovarian cancer, a leading cause of cancer-related deaths among women, comprises distinct subtypes each requiring different treatment approaches. This paper presents a deep-learning framework for classifying ovarian cancer subtypes using Whole Slide I...

Deep learning based on ultrasound images to predict platinum resistance in patients with epithelial ovarian cancer.

Biomedical engineering online
BACKGROUND: The study aimed at developing and validating a deep learning (DL) model based on the ultrasound imaging for predicting the platinum resistance of patients with epithelial ovarian cancer (EOC).

Random forest-based model for the recurrence prediction of borderline ovarian tumor: clinical development and validation.

Journal of cancer research and clinical oncology
PURPOSE: This study aims to develop an effective machine learning (ML)-based predictive model for the recurrence of borderline ovarian tumor (BOT), and provide the guidelines of accurate clinical diagnosis and precise treatment for patients.

Multi-dimensional characterization of cellular states reveals clinically relevant immunological subtypes and therapeutic vulnerabilities in ovarian cancer.

Journal of translational medicine
BACKGROUND: Diverse cell types and cellular states in the tumor microenvironment (TME) are drivers of biological and therapeutic heterogeneity in ovarian cancer (OV). Characterization of the diverse malignant and immunology cellular states that make ...

Mitigation of outcome conflation in predicting patient outcomes using electronic health records.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVES: Artificial intelligence (AI) models utilizing electronic health record data for disease prediction can enhance risk stratification but may lack specificity, which is crucial for reducing the economic and psychological burdens associated w...

Accuracy of Large Language Model-based Automatic Calculation of Ovarian-Adnexal Reporting and Data System MRI Scores from Pelvic MRI Reports.

Radiology
Background Ovarian-Adnexal Reporting and Data System (O-RADS) for MRI helps assign malignancy risk, but radiologist adoption is inconsistent. Automatic assignment of O-RADS scores from reports could increase adoption and accuracy. Purpose To evaluate...

Exploring Ovarian Cancer Prediction Models and Potential Markers Using Machine Learning.

Annals of clinical and laboratory science
OBJECTIVE: To develop machine learning models, facilitate a more accurate diagnosis of ovarian cancer (OC), and explore potential markers.