Genomic alterations are the driving force behind pancreatic cancer (PC) tumorigenesis, but they do not fully account for its diverse phenotypes. Investigating the epigenetic landscapes of PC offers a more comprehensive understanding and could identif...
Pancreatic ductal adenocarcinoma (PDAC) is frequently diagnosed in its late stages when treatment options are limited. Unlike other common cancers, there are no population-wide screening programmes for PDAC. Thus, early disease detection, although ur...
BACKGROUND: Postdischarge venous thromboembolism (pdVTE) is a life-threatening complication following resection for pancreatic cancer (PC). While national guidelines recommend extended chemoprophylaxis for all, adherence is low and ranges from 1.5 to...
Journal of X-ray science and technology
Feb 18, 2025
OBJECTIVE: Early diagnosis of pancreatic cystic neoplasm (PCN) is crucial for patient survival. This study proposes M-YOLO, a novel model combining Mamba architecture and YOLO, to enhance the detection of pancreatic cystic tumors. The model addresses...
BMC medical informatics and decision making
Feb 15, 2025
The diagnosis of pancreatic cancer presents a significant challenge due to the asymptomatic nature of the disease and the fact that it is frequently detected at an advanced stage. This study presents a novel approach combining graph-based data repres...
One bottleneck of magnetic resonance imaging (MRI)-guided online adaptive radiotherapy is the time-consuming daily online replanning process. The current leaf sequencing method takes up to 10 min, with potential dosimetric degradation and small segme...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Jan 31, 2025
PURPOSE: This multicenter study aimed to develop and validate a multiscale deep learning radiomics nomogram for predicting recurrence-free survival (RFS) in patients with pancreatic ductal adenocarcinoma (PDAC).
OBJECTIVES: To evaluate the efficiency of super-resolution deep-learning reconstruction (SR-DLR) optimized for helical body imaging in assessing pancreatic ductal adenocarcinoma (PDAC) using normal-resolution (NR) CT scanner.
To retrospectively develop and validate an interpretable deep learning model and nomogram utilizing endoscopic ultrasound (EUS) images to predict pancreatic neuroendocrine tumors (PNETs). Following confirmation via pathological examination, a retrosp...
United European gastroenterology journal
Jan 26, 2025
The rising incidence of pancreatic diseases, including acute and chronic pancreatitis and various pancreatic neoplasms, poses a significant global health challenge. Pancreatic ductal adenocarcinoma (PDAC) for example, has a high mortality rate due to...
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