AIMC Topic: Porosity

Clear Filters Showing 71 to 80 of 84 articles

Computational intelligence models to predict porosity of tablets using minimum features.

Drug design, development and therapy
The effects of different formulations and manufacturing process conditions on the physical properties of a solid dosage form are of importance to the pharmaceutical industry. It is vital to have in-depth understanding of the material properties and g...

Controlled surface morphology and hydrophilicity of polycaprolactone toward human retinal pigment epithelium cells.

Materials science & engineering. C, Materials for biological applications
Applying scaffolds as a bed to enhance cell proliferation and even differentiation is one of the treatment of retina diseases such as age-related macular degeneration (AMD) which deteriorating photoreceptors and finally happening blindness. In this s...

Determination of the mechanical and physical properties of cartilage by coupling poroelastic-based finite element models of indentation with artificial neural networks.

Journal of biomechanics
One of the most widely used techniques to determine the mechanical properties of cartilage is based on indentation tests and interpretation of the obtained force-time or displacement-time data. In the current computational approaches, one needs to si...

Poroelastic Foams for Simple Fabrication of Complex Soft Robots.

Advanced materials (Deerfield Beach, Fla.)
Open-celled, elastomeric foams allow the simple design of fully 3D pneumatic soft machines using common forming techniques. This is demonstrated through the fabrication of simple actuators and an entirely soft, functional fluid pump formed in the sha...

A methodological evaluation and predictive in silico investigation into the multi-functionality of arginine in directly compressed tablets.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
The acceleration of solid dosage form product development can be facilitated by the inclusion of excipients that exhibit poly-/multi-functionality with reduction of the time invested in multiple excipient optimisations. Because active pharmaceutical ...

Optimal structural characteristics of osteoinductivity in bioceramics derived from a novel high-throughput screening plus machine learning approach.

Biomaterials
Osteoinduction is an important feature of the next generation of bone repair materials. But the key structural factors and parameters of osteoinductive scaffolds are not yet clarified. This study leverages the efficiency of high-throughput screening ...

A Biomimetic Titanium Scaffold With and Without Magnesium Filled for Adjustable Patient-Specific Elastic Modulus.

Journal of biomechanical engineering
This study focuses on determining the effective Young's modulus (stiffness) of various lattice structures for titanium scaffolds filled with magnesium and without magnesium. For a specific patient implant the success depends on adequate elastic modul...

Porous-Structure Flexible Muscle Sensor for Monitoring Muscle Function and Mass.

ACS sensors
Muscle function and composition are important indicators of age-related health. However, current assessment methods are often complex and expensive, making the early detection of related problems difficult. Therefore, developing a cost-effective and ...

Machine learning predictions of drug release from isocyanate-derived aerogels.

Journal of materials chemistry. B
This work utilized machine learning (ML) algorithms to predict and validate the drug release kinetics of a short worm-like nanostructured isocyanate-derived aerogel: the first time ML has been employed to study the drug delivery properties of this i...

An artificial intelligence powered study of enlarged facial pore prevalence on one million Chinese from different age groups and its correlation with environmental factors.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
BACKGROUND: Enlarged pores are amidst one of the top cosmetic concerns, especially among Chinese. Many small-group studies have been conducted in understanding their prevalence and beauty relevance. Nonetheless, population-level investigations are st...