AIMC Topic: Precision Medicine

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AI-driven innovations in smart multifunctional nanocarriers for drug and gene delivery: A mini-review.

Critical reviews in oncology/hematology Mar 13, 2025
The convergence of artificial intelligence (AI) and nanomedicine has revolutionized the design of smart multifunctional nanocarriers (SMNs) for drug and gene delivery, offering unprecedented precision, efficiency, and personalization in therapeutic a...
Animals Nanoparticles Drug Carriers Precision Medicine Drug Delivery Systems Nanomedicine Humans Genetic Therapy Artificial Intelligence Gene Transfer Techniques
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Control of medical digital twins with artificial neural networks.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences Mar 13, 2025
The objective of precision medicine is to tailor interventions to an individual patient's unique characteristics. A key technology for this purpose involves medical digital twins, computational models of human biology that can be personalized and dyn...
Stochastic Processes Uncertainty Precision Medicine Models, Biological Humans Neural Networks, Computer Computer Simulation
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Special issue European Journal of Physiology: Artificial intelligence in the field of physiology and medicine.

Pflugers Archiv : European journal of physiology Mar 11, 2025
This special issue presents a collection of reviews on the recent advancements and applications of artificial intelligence (AI) in medicine and physiology. The topics covered include digital histopathology, generative AI, explainable AI (XAI), and et...
Artificial Intelligence Precision Medicine Animals Physiology Humans
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Sensing the Future of Thrombosis Management: Integrating Vessel-on-a-Chip Models, Advanced Biosensors, and AI-Driven Digital Twins.

ACS sensors Mar 11, 2025
Thrombotic events, such as strokes and deep vein thrombosis, remain a significant global health burden, with traditional diagnostic methods often failing to capture the complex, patient-specific nuances of thrombosis risk. This Perspective explores t...
Humans Artificial Intelligence Thrombosis Precision Medicine Lab-On-A-Chip Devices Biosensing Techniques
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Innovative construction and application of bile duct organoids: Unraveling the complexity of bile duct diseases and potential therapeutic strategies.

Cancer letters Mar 10, 2025
The biliary system is crucial for liver function, regulating bile production, secretion, and transport. Dysfunctions within this system can lead to various diseases, such as cholangiopathies and biliary fibrosis, which may progress from benign to mal...
Tissue Engineering Bile Duct Diseases Organoids Regenerative Medicine Bile Ducts Humans Precision Medicine Animals
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Cancer Drug Sensitivity Prediction Based on Deep Transfer Learning.

International journal of molecular sciences Mar 10, 2025
In recent years, many approved drugs have been discovered using phenotypic screening, which elaborates the exact mechanisms of action or molecular targets of drugs. Drug susceptibility prediction is an important type of phenotypic screening. Large-sc...
Cell Line, Tumor Neoplasms Drug Resistance, Neoplasm Humans Computational Biology Antineoplastic Agents Precision Medicine Drug Screening Assays, Antitumor Deep Learning
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Equitable machine learning counteracts ancestral bias in precision medicine.

Nature communications Mar 10, 2025
Gold standard genomic datasets severely under-represent non-European populations, leading to inequities and a limited understanding of human disease. Therapeutics and outcomes remain hidden because we lack insights that could be gained from analyzing...
Genomics Machine Learning Precision Medicine Female Breast Neoplasms Humans Neoplasms Phylogeny
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Harnessing Artificial Intelligence for Precision Diagnosis and Treatment of Triple Negative Breast Cancer.

Clinical breast cancer Mar 8, 2025
Triple-Negative Breast Cancer (TNBC) is a highly aggressive subtype of breast cancer (BC) characterized by the absence of estrogen, progesterone, and HER2 receptors, resulting in limited therapeutic options. This article critically examines the role ...
Female Biomarkers, Tumor Triple Negative Breast Neoplasms Humans Artificial Intelligence Precision Medicine
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AI-Driven decision-making for personalized elderly care: a fuzzy MCDM-based framework for enhancing treatment recommendations.

BMC medical informatics and decision making Mar 8, 2025
BACKGROUND: Global healthcare systems face enormous challenges due to the ageing population, demanding novel measures to assure long-term efficacy and viability. The expanding senior population, which requires specialised and efficient healthcare sol...
Clinical Decision-Making Aged Fuzzy Logic Patient-Centered Care Artificial Intelligence Precision Medicine Electronic Health Records Humans
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Development of a MVI associated HCC prognostic model through single cell transcriptomic analysis and 101 machine learning algorithms.

Scientific reports Mar 7, 2025
Hepatocellular carcinoma (HCC) is an exceedingly aggressive form of cancer that often carries a poor prognosis, especially when it is complicated by the presence of microvascular invasion (MVI). Identifying patients at high risk of MVI is crucial for...
Clinical Decision-Making Biomarkers, Tumor Risk Assessment Precision Medicine Prognosis Immunotherapy Gene Expression Regulation, Neoplastic Treatment Outcome Liver Neoplasms Carcinoma, Hepatocellular Single-Cell Gene Expression Analysis Humans Machine Learning Kaplan-Meier Estimate Microvessels Immune Checkpoint Proteins Meta-Analysis as Topic Mutation Datasets as Topic Neoplasm Invasiveness Liver
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